ERF Antibody (PACO21790)
- SKU:
- PACO21790
Description
| Antibody Name: | ERF Antibody (PACO21790) |
| Antibody SKU: | PACO21790 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human ERF. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen Olsen J.V., Cell 127:635-648(2006). |
| Clonality: | Polyclonal |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using ERF antibody. |
| Synonyms: | ETS-domain transcription factor ERF; Ets2 repressor factor; |
| UniProt Protein Function: | ERF: potent transcriptional repressor that binds to the H1 element of the ETS2 promoter. Belongs to the ETS family of transcription factors. Its function is regulated by phosphorylation. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 19q13 Cellular Component: cytosol; Golgi apparatus; nucleoplasm; nucleus Molecular Function:sequence-specific DNA binding; transcription corepressor activity Biological Process: cell cycle; cell differentiation; negative regulation of transcription from RNA polymerase II promoter; transcription, DNA-dependent Disease: Craniosynostosis 4 |
| NCBI Summary: | ETS2 is a transcription factor and protooncogene involved in development, apoptosis, and the regulation of telomerase. The protein encoded by this gene binds to the ETS2 promoter and is a strong repressor of ETS2 transcription. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P50548 |
| NCBI GenInfo Identifier: | 50403684 |
| NCBI Gene ID: | 2077 |
| NCBI Accession: | P50548.2 |
| UniProt Secondary Accession: | P50548,Q59G38, Q9UPI7, B2RAP1, B7Z4R0, |
| UniProt Related Accession: | P50548 |
| Molecular Weight: | 49,965 Da |
| NCBI Full Name: | ETS domain-containing transcription factor ERF |
| NCBI Synonym Full Names: | ETS2 repressor factor |
| NCBI Official Symbol: | ERF |
| NCBI Official Synonym Symbols: | PE2; CRS4; PE-2 |
| NCBI Protein Information: | ETS domain-containing transcription factor ERF |
| UniProt Protein Name: | ETS domain-containing transcription factor ERF |
| UniProt Synonym Protein Names: | Ets2 repressor factor; PE-2 |
| Protein Family: | Essential recombination function protein |
| UniProt Gene Name: | ERF |
| UniProt Entry Name: | ERF_HUMAN |
| Antibodies | ELISA Kits |
| Phospho-ERF (T526) Antibody (PACO03638) | ERF Transcription Factor Activity Assay |
| ERF Antibody (PACO03639) | |
| ERF Antibody (PACO06474) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Additional Information
Product Type: |
Antibody |
Reactivity: |
Human |
Reactivity: |
Mouse |
Host Species: |
Rabbit |
Isotype: |
IgG |
Applications: |
ELISA |
Applications: |
IHC |
Antibody Type: |
Polyclonal Antibody |
Conjugation: |
Unconjugated |
