| UniProt Protein Function: | ERas: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. Belongs to the small GTPase superfamily. Ras family.Protein type: G protein, monomeric, Ras; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: Xp11.23 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q7Z444 |
| NCBI GenInfo Identifier: | 74723320 |
| NCBI Gene ID: | 3266 |
| NCBI Accession: | Q7Z444.1 |
| UniProt Secondary Accession: | Q7Z444 |
| UniProt Related Accession: | Q7Z444 |
| Molecular Weight: | 25,287 Da |
| NCBI Full Name: | GTPase ERas |
| NCBI Synonym Full Names: | ES cell expressed Ras |
| NCBI Official Symbol: | ERAS |
| NCBI Official Synonym Symbols: | HRAS2; HRASP |
| NCBI Protein Information: | GTPase ERas |
| UniProt Protein Name: | GTPase ERas |
| UniProt Synonym Protein Names: | Embryonic stem cell-expressed Ras |
| Protein Family: | GTPase |
| UniProt Gene Name: | ERAS |
| UniProt Entry Name: | RASE_HUMAN |