ERAS Antibody (PACO19614)
- SKU:
- PACO19614
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ERAS Antibody (PACO19614) |
| Antibody SKU: | PACO19614 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000, IHC:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human ERAS |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO19614(ERAS Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue, Primary antibody: PACO19614(ERAS Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19614(ERAS Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. |
| Synonyms: | ES cell expressed Ras |
| UniProt Protein Function: | ERas: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity. Plays an important role in the tumor-like growth properties of embryonic stem cells. Belongs to the small GTPase superfamily. Ras family.Protein type: G protein, monomeric, Ras; G protein, monomeric; G proteinChromosomal Location of Human Ortholog: Xp11.23 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012] |
| UniProt Code: | Q7Z444 |
| NCBI GenInfo Identifier: | 74723320 |
| NCBI Gene ID: | 3266 |
| NCBI Accession: | Q7Z444.1 |
| UniProt Secondary Accession: | Q7Z444 |
| UniProt Related Accession: | Q7Z444 |
| Molecular Weight: | 25,287 Da |
| NCBI Full Name: | GTPase ERas |
| NCBI Synonym Full Names: | ES cell expressed Ras |
| NCBI Official Symbol: | ERAS |
| NCBI Official Synonym Symbols: | HRAS2; HRASP |
| NCBI Protein Information: | GTPase ERas |
| UniProt Protein Name: | GTPase ERas |
| UniProt Synonym Protein Names: | Embryonic stem cell-expressed Ras |
| Protein Family: | GTPase |
| UniProt Gene Name: | ERAS |
| UniProt Entry Name: | RASE_HUMAN |
| Antibodies |
| ERAS Antibody (PACO04072) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
