Equine IFN g Recombinant Protein (RPPB0403)

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SKU:
RPPB0403
Product Type:
Recombinant Protein
Species:
Horse
Uniprot:
P42160

Description

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Product Name:Equine IFN g Recombinant Protein
Product Code:RPPB0403
Size:20µg
Species:Equine
Target:IFN g
Synonyms:Interferon gamma, IFN-gamma, IFNG.
Source:Escherichia Coli
Physical Appearance:Sterile Filtered White lyophilized (freeze-dried) powder.
Formulation:Lyophilized from a 0.2�m filtered concentrated solution in PBS, pH 7.4 and 5% trehalose.
Solubility:It is recommended to reconstitute the lyophilized Interferon-gamma in sterile 18M-cm H2O not less than 100�g/ml, which can then be further diluted to other aqueous solutions.
Stability:Lyophilized Interferon-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IFN-gamma should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Purity:Greater than 97.0% as determined by:(a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Amino Acid Sequence:QAAFFKEIEN LKEYFNASNP DVGDGGPLFL DILKNWKEDS DKKIIQSQIV SFYFKLFENL KDNQVIQKSM DTIKEDLFVK FFNSSTSKLE DFQKLIQIPV NDLKVQRKAI SELIKVMNDL SPKANLRKRK RSQNPFRGRR ALQ
Biological Activity:The ED50 as determined by an anti-viral assay using human HeLa cells infected with encephalomyocarditis (EMC) virus is less than 10.0 ng/ml, corresponding to a specific activity of > 1.0 � 105 IU/mg.

IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.

Recombinant Equine Interferon-gamma produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 143 amino acids and having a molecular mass of 16.7kDa.The IFN-gamma Equine is purified by proprietary chromatographic techniques.

UniProt Protein Function:Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
UniProt Code:P42160
NCBI GenInfo Identifier:1170561
NCBI Gene ID:100034181
NCBI Accession:P42160.1
UniProt Secondary Accession:P42160,Q28387,
UniProt Related Accession:P42160
Molecular Weight:19,338 Da
NCBI Full Name:Interferon gamma
NCBI Official Symbol:IFNG��
NCBI Protein Information:interferon gamma
UniProt Protein Name:Interferon gamma
Protein Family:Interferon
UniProt Gene Name:IFNG��
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