EPS8L1 Antibody (PACO23270)
- SKU:
- PACO23270
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EPS8L1 Antibody (PACO23270) |
| Antibody SKU: | PACO23270 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IHC:1:50-1:100 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human ES8L1. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from COLO205 cells, using ES8L1 antibody. |
 | Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue using ES8L1 antibody. |
| Background: | Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. |
| Synonyms: | Epidermal growth factor receptor kinase substrate 8-like protein 1; Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-like protein 1; EPS8L1; DRC3 |
| UniProt Protein Function: | EPS8L1: Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. Belongs to the EPS8 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 19q13.42 Cellular Component: cytoplasm; protein complex Molecular Function:actin binding; protein binding; Rac guanyl-nucleotide exchange factor activity; Rho guanyl-nucleotide exchange factor activity; T cell receptor binding Biological Process: regulation of Rho protein signal transduction; Rho protein signal transduction |
| NCBI Summary: | This gene encodes a protein that is related to epidermal growth factor receptor pathway substrate 8 (EPS8), a substrate for the epidermal growth factor receptor. The function of this protein is unknown. At least two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8TE68 |
| NCBI GenInfo Identifier: | 296439363 |
| NCBI Gene ID: | 54869 |
| NCBI Accession: | Q8TE68.3 |
| UniProt Secondary Accession: | Q8TE68,Q71RE2, Q8NC10, Q96BB7, Q9BSQ2, Q9GZQ2, Q9NXH0 |
| UniProt Related Accession: | Q8TE68 |
| Molecular Weight: | 55,807 Da |
| NCBI Full Name: | Epidermal growth factor receptor kinase substrate 8-like protein 1 |
| NCBI Synonym Full Names: | EPS8 like 1 |
| NCBI Official Symbol: | EPS8L1 |
| NCBI Official Synonym Symbols: | DRC3; EPS8R1; PP10566 |
| NCBI Protein Information: | epidermal growth factor receptor kinase substrate 8-like protein 1 |
| UniProt Protein Name: | Epidermal growth factor receptor kinase substrate 8-like protein 1 |
| UniProt Synonym Protein Names: | Epidermal growth factor receptor pathway substrate 8-related protein 1; EPS8-related protein 1 |
| Protein Family: | Epidermal growth factor receptor kinase substrate 8-like protein |
| UniProt Gene Name: | EPS8L1 |
| UniProt Entry Name: | ES8L1_HUMAN |
| Antibodies | ELISA Kits |
| EPS8L1 Antibody (PACO00771) | ES8L1 Colorimetric Cell-Based ELISA |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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