Epigenetics & Nuclear Signaling Recombinant Proteins

system_update_altDatasheetDNA Polymerase Beta/POLB Recombinant Protein Human DNA polymerase β is constitutively expressed in cells. It fills in gaps in DNA that are formed following base...

system_update_altDatasheetER alpha Recombinant Protein Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is...

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system_update_altDatasheetHuman APE1/APE Recombinant Protein The enzyme is known to be a redox factor (Ref-1) stimulating DNA binding activity of AP-1 binding proteins such as Fos and Jun as well as...

system_update_altDatasheetHuman ASF1A Recombinant Protein Human Histone Chaperone ASF1A (ASF1A) belongs to the H3/H4 family of histone chaperone proteins. ASF1A is ubiquitously expressed in many...

system_update_altDatasheetHuman ASXL1 Recombinant Protein Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as...

system_update_altDatasheetHuman ATF1 Recombinant Protein Cyclic AMP-dependent transcription factor ATF-1(ATF1) which contains 1 bZIP (basic-leucine zipper) domain and 1 KID (kinase-inducible) domain,...

system_update_altDatasheetHuman ATF2 Recombinant Protein Activating transcription factor 2, also known as ATF2, is a member of the leucine zipper family of DNA-binding proteins that binds to the cAMP...

system_update_altDatasheetHuman BCAS2/DAM1 Recombinant Protein Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many...

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system_update_altDatasheetHuman Cyclophilin E/PPIE Recombinant Protein Peptidyl-prolyl cis-trans isomerase E, also known as Cyclophilin E, Cyclophilin-33, Rotamase E, CYP33, PPIE, is an enzyme which...

system_update_altDatasheetHuman EBP1/PA2G4 Recombinant Protein EBP1, also known as PA2G4, is an RNA-binding protein which belongs to the peptidase M24 family. It can be detected n several cell lines...

system_update_altDatasheetHuman EIF5A2 Recombinant Protein EIF5A2 is a member of the eIF-5A family. It is a 153 amino acids protein that in humans is encoded by the EIF5A2 gene. EIF5A2 is expressed...

system_update_altDatasheetHuman ELK1 Recombinant Protein E twenty-six (ETS)-like transcription factor 1, also known as Elk1 or Member of ETS oncogene family (ELK1), is a member of the ETS oncogene...

system_update_altDatasheetHuman Fumarase/FH Recombinant Protein Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of...

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system_update_altDatasheetHuman HDGF Recombinant Protein Hepatoma-Derived Growth Factor is a original member of the HDGF family. HDGF is a cytoplasmic protein and contains one PWWP domain. HDGF...

system_update_altDatasheetHuman HER2/ErbB2 Recombinant Protein Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein; and belongs to the epidermal growth factor (EGF)...

system_update_altDatasheetHuman HER2/ErbB2 Recombinant Protein Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein; and belongs to the epidermal growth factor (EGF)...

system_update_altDatasheetHuman HIF alpha/HIF1A Recombinant Protein HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain and 2...

system_update_altDatasheetHuman HOXA1 Recombinant Protein Homeobox protein Hox-A1 is a transcription factor encoded by HOXA1 gene. This gene is one of the four types of homeobox genes each of which...

system_update_altDatasheetHuman HOXB4 Recombinant Protein Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear...

system_update_altDatasheetHuman IA2/PTPRN Recombinant Protein Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8...

system_update_altDatasheetHuman IA2/PTPRN Recombinant Protein Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8...

system_update_altDatasheetHuman IA2/PTPRN Recombinant Protein Receptor-type tyrosine-protein phosphatase-like N (PTPRN) belongs to the protein-tyrosine phosphatase family and receptor class 8...

system_update_altDatasheetHuman IGF2BP2 Recombinant Protein Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 (IGFBP2) belongs to the RRM IMP/VICKZ family. IGFBP2 is a cytoplasmic protein and...

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system_update_altDatasheetHuman LSM1 Recombinant Protein U6 snRNA-Associated Sm-Like Protein LSm1 (LSM1) belongs to the snRNP Sm proteins family. The Sm-like proteins are thought to form a stable...

system_update_altDatasheetHuman LSM4 Recombinant Protein U6 snRNA-associated Sm-like protein LSm4 (LSM4) is a member of the snRNP Sm proteins family. Sm-like proteins contain the Sm sequence motif...

system_update_altDatasheetHuman MECP2 Recombinant Protein The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes...

system_update_altDatasheetHuman MGMT Recombinant Protein MGMT belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. MGMT involved in the cellular...

system_update_altDatasheetHuman MORF4L2/MRGX Recombinant Protein Mortality Factor 4-Like Protein 2 (MORF4L2) is a member of the mortality factor (MORF) family. MORF4L2 localizes in the nucleus,...

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system_update_altDatasheetHuman NLK Recombinant Protein Nemo-like kinase contains 1 protein kinase domain and belongs to the protein kinase superfamily, CMGC Ser/Thr protein kinase family and MAP...

system_update_altDatasheetHuman PARP-3/PARP3 Recombinant Protein Regenerating islet-derived protein 4, also known as REG-like protein, REG4, GISP and RELP, a member of the regenerating gene family...

system_update_altDatasheetHuman PCNA Recombinant Protein Proliferating Cell Nuclear Antigen (PCNA) is a protein only expresse in nomal proliferate cells and cancer cells. It is central to both DNA...

system_update_altDatasheetHuman POLD2 Recombinant Protein DNA Polymerase Delta Subunit 2 (POLD2) belongs to the DNA polymerase delta/II small subunit family. POLD2 can form a heterotetramer composed...

system_update_altDatasheetHuman PPIase/FKBP7 Recombinant Protein PPIase is a member of the immunophilin protein family. It also belongs to the cyclophilin-type PPIase family; PPIL3 subfamily. PPIase...

system_update_altDatasheetHuman PPIase/PPIL1 Recombinant Protein Peptidyl-Prolyl Cis-Trans Isomerase-Like 1 (PPIase) belongs to the cyclophilin-type PPIase family. PPIases can accelerate the folding...

system_update_altDatasheetHuman PPIH Recombinant Protein Peptidyl-Prolyl Cis-Trans Isomerase H (PPIH) belongs to the Cyclophilin-type PPIase family that accelerate the folding of proteins. PPIases...

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system_update_altDatasheetHuman PRPS2 Recombinant Protein Ribose-Phosphate Pyrophosphokinase 2 (PRPS2) is a phosphoribosyl pyrophosphate synthetase that belongs to the ribose-phosphate...

system_update_altDatasheetHuman PYM1/WIBG Recombinant Protein Partner of Y14 and Mago (WIBG) is a key regulator of the Exon Junction Complex (EJC). EJC is a multiprotein complex that associates...

system_update_altDatasheetHuman RRM2B/P53R2 Recombinant Protein Ribonucleoside reductase subunit M2B, also known as RRM2B or p53R2, is an enzyme belonging to the iron-dependent ribonucleotide...

system_update_altDatasheetHuman SENP2 Recombinant Protein SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway:...

system_update_altDatasheetHuman SMAD1 Recombinant Protein SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle,...

system_update_altDatasheetHuman SMAD4 Recombinant Protein SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain...

system_update_altDatasheetHuman SNU13 Recombinant Protein NHP2-Like Protein 1 (NHP2L1) is a member of the ribosomal protein L7Ae family. NHP2L1 proteinis limited to the nucleus, primarily focused in...

system_update_altDatasheetHuman STAT5B Recombinant Protein Signal Transducer and Activator of Transcription 5b (STAT5B) is a member of the STAT family of transcription factors. They are responsible...

system_update_altDatasheetHuman STAT6 Recombinant Protein Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced...

system_update_altDatasheetHuman STAT6 Recombinant Protein Signal Transducer and Activator of Transcription 6 (STAT6) is a member of the STAT family of transcription factors. At least seven STATs...

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system_update_altDatasheetHuman TAOK3/JIK/MAP3K18 Recombinant Protein Serine/threonine-protein kinase TAO3, also known as cutaneous T-cell lymphoma-associated antigen HD-CL-09, CTCL-associated...

system_update_altDatasheetHuman TFAP2C/AP2-GAMMA Recombinant Protein TFAP2C, also known as AP2-GAMMA, is a member of the activating protein 2 family of transcription factors. AP-2 factors bind to the...

system_update_altDatasheetHuman TK1 Recombinant Protein Thymidine kinase 1(TK1) belongs to the thymidine kinase family. It is located in the cytoplasm, and phosphorylated on Ser-13 in mitosis during...

system_update_altDatasheetHuman TLE3 Recombinant Protein Immunoglobulin superfamily member 11(IGSF11) are expressed on the plasma membrane in the tesis and brain. These IGSF proteins undergo final...

system_update_altDatasheetHuman TSC22D1 Recombinant Protein TSC22 domain family, member 1 (TSC22D1) is one of the TGF-beta-stimulated clone-22 (TSC-22). TSC-22 was reported to be a...

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system_update_altDatasheetHuman UBE2A Recombinant Protein Ubiquitin-conjugating enzyme E2 A (also known as HHR6A or UBE2A); encoded by human DNA repair genes HHR6A; belongs to the...

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system_update_altDatasheetHuman UBE2B/HR6B Recombinant Protein Ubiquitin-Conjugating Enzyme E2 B (UBE2B) is a member of the ubiquitin-conjugating enzyme family. UBE2B accepts ubiquitin from the E1...

system_update_altDatasheetHuman UBE2T Recombinant Protein Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the...

system_update_altDatasheetHuman UBE2T Recombinant Protein Ube2T is the E2 ubiquitin-conjugating enzyme of the Fanconi anemia DNA repair pathway and it is overexpressed in several cancers;...

system_update_altDatasheetHuman UBE2W Recombinant Protein Ubiquitin-conjugating enzymes, also known as UBE2W, E2 enzymes and more rarely as ubiquitin-carrier enzymes, perform the second step of...

system_update_altDatasheetHuman VDR/NR1I1 Recombinant Protein VDR (vitamin D(1,25- dihydroxyvitamin D3)receptor), also known as NR1I1, belongs to the NR1I family, NR1 subfamily. It is composed of...

system_update_altDatasheetHuman ZBTB17/Miz Recombinant Protein Zinc Finger and BTB Domain-Containing Protein 17 (ZBTB17) belongs to the Kruppel C2H2-type zinc finger protein family. ZBTB17 may...

system_update_altDatasheetHuman ZNF70 Recombinant Protein Zinc Finger Protein 70 (ZNF70) is a member of the krueppel C2H2-type zinc-finger protein family. ZFN70 is localized to the cell nucleus and...

system_update_altDatasheetHuman ZNF75A Recombinant Protein Zinc Finger Protein 75A (ZNF75A) is a member of krueppel C2H2-type zinc-finger protein family. The human ZNF75 gene is located on Xq26,...

system_update_altDatasheetMouse HER2/ErbB2 Recombinant Protein Epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the...

system_update_altDatasheetMouse HER2/ErbB2 Recombinant Protein Epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein, and belongs to the...

system_update_altDatasheetMouse SMAD3 Recombinant Protein SMAD3 belongs to the SMAD family. Members of this family mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily...

system_update_altDatasheetMouse VDR/NR1I1 Recombinant Protein VDR (vitamin D(1,25- dihydroxyvitamin D3)receptor), also known as NR1I1, belongs to the NR1I family, NR1 subfamily. It is composed of...

system_update_altDatasheetRat HER2/ErbB2 Recombinant Protein ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain...

system_update_altDatasheetThymidylate Kinase/DTYMK Recombinant Protein Thymidylate kinase (DTYMK) is a ubiquitous enzyme of about 25 kD which belongs to thymidylate kinase family. DTYMK is important...

system_update_altDatasheetUracil-DNA glycosylase/UNG Recombinant Protein Isoform 1 is widely expressed with the highest expression in skeletal muscle, heart and testicles. Isoform 2 has the highest...