EPHA6 Antibody (PACO56226)
- SKU:
- PACO56226
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EPHA6 Antibody (PACO56226) |
| Antibody SKU: | PACO56226 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Ephrin type-A receptor 6 protein (132-279AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO56226 diluted at 1:200 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | IHC image of PACO56226 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity). |
| Synonyms: | Ephrin type-A receptor 6 (EC 2.7.10.1) (EPH homology kinase 2) (EHK-2) (EPH-like kinase 12) (EK12), EPHA6, EHK2 HEK12 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9UF33 |
| NCBI GenInfo Identifier: | 341940657 |
| NCBI Gene ID: | 13840 |
| NCBI Accession: | Q62413.2 |
| UniProt Secondary Accession: | Q9UF33,P54758, Q9UF33 |
| UniProt Related Accession: | Q9UF33,Q62413 |
| Molecular Weight: | 116,185 Da |
| NCBI Full Name: | Ephrin type-A receptor 6 |
| NCBI Synonym Full Names: | Eph receptor A6 |
| NCBI Official Symbol: | Epha6 |
| NCBI Official Synonym Symbols: | Ehk2; Hek12; m-ehk2 |
| NCBI Protein Information: | ephrin type-A receptor 6; EHK-2; EPH homology kinase 2 |
| UniProt Protein Name: | Ephrin type-A receptor 6 |
| UniProt Synonym Protein Names: | EPH homology kinase 2; EHK-2 |
| Protein Family: | Ephrin type-A receptor |
| UniProt Gene Name: | Epha6 |
| UniProt Entry Name: | EPHA6_MOUSE |
| Antibodies |
| EPHA6 Antibody (PACO03942) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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