EPGN Antibody (PACO19608)
- SKU:
- PACO19608
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EPGN Antibody (PACO19608) |
| Antibody SKU: | PACO19608 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthetic peptide of human EPGN |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Jurkat cells, 293T cells, hela cells, Primary antibody: PACO19608(EPGN Antibody) at dilution 1/150, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute. |
| Background: | The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. |
| Synonyms: | epithelial mitogen |
| UniProt Protein Function: | Epigen: Promotes the growth of epithelial cells. May stimulate the phosphorylation of EGFR and mitogen-activated protein kinases. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Ligand, receptor tyrosine kinaseChromosomal Location of Human Ortholog: 4q13.3Cellular Component: extracellular space; integral to plasma membrane; intracellularMolecular Function: epidermal growth factor receptor binding; growth factor activityBiological Process: activation of MAPK activity; angiogenesis; epidermal growth factor receptor signaling pathway; MAPKKK cascade; positive regulation of cell proliferation; positive regulation of epidermal growth factor receptor activity; positive regulation of epithelial cell proliferation; positive regulation of MAP kinase activity; positive regulation of mitosis |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012] |
| UniProt Code: | Q6UW88 |
| NCBI GenInfo Identifier: | 229464464 |
| NCBI Gene ID: | 255324 |
| NCBI Accession: | Q6UW88.2 |
| UniProt Secondary Accession: | Q6UW88,A1BMM3, A1BMM4, A1BMM5, A1BMM6, A1BMM7, A1BMM8 A8K090 |
| UniProt Related Accession: | Q6UW88 |
| Molecular Weight: | |
| NCBI Full Name: | Epigen |
| NCBI Synonym Full Names: | epithelial mitogen |
| NCBI Official Symbol: | EPGN |
| NCBI Official Synonym Symbols: | EPG; PRO9904; ALGV3072 |
| NCBI Protein Information: | epigen |
| UniProt Protein Name: | Epigen |
| UniProt Synonym Protein Names: | Epithelial mitogen; EPG |
| Protein Family: | Epigen |
| UniProt Gene Name: | EPGN |
| UniProt Entry Name: | EPGN_HUMAN |
| Antibodies |
| EPGN Antibody (PACO06928) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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