EPCR/CD201 Monoclonal Antibody (CAB24229)
- SKU:
- CAB24229
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- FC
- Applications:
- WB
Description
| Product Name: | EPCR/CD201 Monoclonal Antibody |
| Product Code: | CAB24229 |
| Reactivity: | Human, Mouse |
| Applications: | Flow Cytometry, Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC60942 |
| Reactivity: | Human, Mouse |
| Tested Applications: | WB, FC, ELISA |
| Key Applications: | Flow Cytometry, Western blotting |
| Recommended Dilution: | FC 1:100-1:500, WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | Mouse spleen |
| Cellular Location: | Membrane, Single-pass type I membrane protein |
The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 18-210 of human CD201/EPCR (NP_006395.2). |
| Sequence: | QDASD GLQRL HMLQI SYFRD PYHVW YQGNA SLGGH LTHVL EGPDT NTTII QLQPL QEPES WARTQ SGLQS YLLQF HGLVR LVHQE RTLAF PLTIR CFLGC ELPPE GSRAH VFFEV AVNGS SFVSF RPERA LWQAD TQVTS GVVTF TLQQL NAYNR TRYEL REFLE DTCVQ YVQKH ISAEN TKGSQ TSRSY TS |
| Synonyms: | PROCR, CCCA, CCD41, EPCR, protein C receptor |
| Calculated MW: | 26kDa |
| Observed MW: | 49kDa |
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