EPCAM Monoclonal Antibody [PAT36F10AT] (CPAB0608)
![EPCAM Monoclonal Antibody [PAT36F10AT] (CPAB0608)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/608x608/products/58828/64010/assay-genie-box-4__66682.1706535229.jpg?c=1 "EPCAM Monoclonal Antibody [PAT36F10AT] (CPAB0608)")
- SKU:
- CPAB0608
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Universal
- Host Species:
- Mouse
- Isotype:
- IgG1
- Clone:
- PAT36F10AT
- Applications:
- WB
- Applications:
- ELISA
![EPCAM Monoclonal Antibody [PAT36F10AT] (CPAB0608)](https://cdn11.bigcommerce.com/s-rd6ounxcu2/images/stencil/1280x1280/products/58828/64010/assay-genie-box-4__66682.1706535229.jpg?c=1&imbypass=on "EPCAM Monoclonal Antibody [PAT36F10AT] (CPAB0608)")
Description
system_update_alt Datasheet
| Product Name: | EPCAM Antibody |
| Product Sku: | CPAB0608 |
| Size: | 5μg |
| Host Species: | Mouse |
| Immunogen: | Anti-human EPCAM mAb, clone PAT37F9AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human EPCAM protein 24-265 amino acids purified from Ecoli. |
| Clone: | PAT36F10AT. |
| Reactivity: | Other bodies |
| Applications: | Western Blot, ELISA |
| Purification Method: | EPCAM antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
| Isotype: | IgG1 |
| Background: | EPCAM is a carcinoma-associated antigen and belongs to a family which includes at least 2 type I membrane proteins. The EPCAM protein has a role in embryonic stem cells proliferation and differentiation. EPCAM is used as a target for immunotherapy treatment of human carcinomas. EPCAM is expressed on most normal epithelial cells and gastrointestinal carcinomas and acts as a homotypic calcium-independent cell adhesion molecule. Epithelial cell adhesion molecules (EPCAM) can act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for supplying immunological barrier as a first line of defense against mucosal infection. EPCAM gene mutations result in congenital tufting enteropathy. |
| Synonyms: | Epithelial cell adhesion molecule, Ep-CAM, Adenocarcinoma-associated antigen, Cell surface glycoprotein Trop-1, Epithelial cell surface antigen, Epithelial glycoprotein, EGP, Epithelial glycoprotein 314, EGP314, hEGP314, KS 1/4 antigen, KSA, Major gastrointestinal tumor-associated protein GA733-2, Tumor-associated calcium signal transducer 1, CD326, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1, ESA, MK-1, DIAR5, EGP-2, EGP40, KS1/4, HNPCC8. |
| Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |
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