Description
Product Name: | EpCAM Monoclonal Antibody |
Product Code: | CAB23075 |
Reactivity: | Human |
Applications: | Western blotting, Immunohistochemistry |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC57675 |
Reactivity: | Human |
Tested Applications: | WB, IHC-P, ELISA |
Key Applications: | Western blotting, Immunohistochemistry |
Recommended Dilution: | WB 1:10000-1:40000, IHC-P 1:50-1:200 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | A-431, HCT116 |
Cellular Location: | Cell junction, Lateral cell membrane, Single-pass type I membrane protein, tight junction |
This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy.
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 24-265 of human EpCAM (NP_002345.2). |
Sequence: | QEECV CENYK LAVNC FVNNN RQCQC TSVGA QNTVI CSKLA AKCLV MKAEM NGSKL GRRAK PEGAL QNNDG LYDPD CDESG LFKAK QCNGT SMCWC VNTAG VRRTD KDTEI TCSER VRTYW IIIEL KHKAR EKPYD SKSLR TALQK EITTR YQLDP KFITS ILYEN NVITI DLVQN SSQKT QNDVD IADVA YYFEK DVKGE SLFHS KKMDL TVNGE QLDLD PGQTL IYYVD EKAPE FSMQG LK |
Synonyms: | ESA, KSA, M4S1, MK-1, DIAR5, EGP-2, EGP40, KS1/4, MIC18, TROP1, BerEp4, EGP314, HNPCC8, LYNCH8, MOC-31, Ber-Ep4, TACSTD1 |
Calculated MW: | 35kDa |
Observed MW: | 40kDa |