ENY2 Antibody (PACO42214)
- SKU:
- PACO42214
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ENY2 Antibody (PACO42214) |
| Antibody SKU: | PACO42214 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Transcription and mRNA export factor ENY2 protein (1-101AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. |
| Synonyms: | Transcription and mRNA export factor ENY2 (Enhancer of yellow 2 transcription factor homolog), ENY2 |
| UniProt Protein Function: | |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9NPA8 |
| NCBI GenInfo Identifier: | 9910186 |
| NCBI Gene ID: | 56943 |
| NCBI Accession: | NP_064574.1 |
| UniProt Secondary Accession: | Q9NPA8,B2RE52, G3V117 |
| UniProt Related Accession: | Q9NPA8 |
| Molecular Weight: | 10,984 Da |
| NCBI Full Name: | transcription and mRNA export factor ENY2 isoform 1 |
| NCBI Synonym Full Names: | enhancer of yellow 2 homolog (Drosophila) |
| NCBI Official Symbol: | ENY2 |
| NCBI Official Synonym Symbols: | DC6; e(y)2 |
| NCBI Protein Information: | transcription and mRNA export factor ENY2; enhancer of yellow 2 transcription factor homolog |
| UniProt Protein Name: | Transcription and mRNA export factor ENY2 |
| UniProt Synonym Protein Names: | Enhancer of yellow 2 transcription factor homolog |
| Protein Family: | Transcription and mRNA export factor |
| UniProt Gene Name: | ENY2 |
| UniProt Entry Name: | ENY2_HUMAN |
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