ENTR1 Antibody (PACO57956)
- SKU:
- PACO57956
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ENTR1 Antibody (PACO57956) |
| Antibody SKU: | PACO57956 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Endosome-associated-trafficking regulator 1 protein (121-230AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | IHC image of PACO57956 diluted at 1:300 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
 | Immunofluorescence staining of HepG2 cells with PACO57956 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | IHC image of PACO57956 diluted at 1:300 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
| Background: | Endosome-associated protein that plays a role in membrane receptor sorting, cytokinesis and ciliogenesis. Involved in the endosome-to-plasma membrane trafficking and recycling of SNX27-retromer-dependent cargo proteins, such as GLUT1. Involved in the regulation of cytokinesis; the function may involve PTPN13 and GIT1. Plays a role in the formation of cilia. Involved in cargo protein localization, such as PKD2, at primary cilia. Involved in the presentation of the tumor necrosis factor (TNF) receptor TNFRSF1A on the cell surface, and hence in the modulation of the TNF-induced apoptosis (By similarity). |
| Synonyms: | Endosome-associated-trafficking regulator 1 (Antigen NY-CO-3) (Serologically defined colon cancer antigen 3), ENTR1, SDCCAG3 |
| UniProt Protein Function: | SDCCAG3: May be involved in modulation of TNF response. May be involved in presentation of TNFRSF1A on the cell surface. Belongs to the SDCCAG3 family. 4 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Chromosomal Location of Human Ortholog: 9q34.3 Cellular Component: recycling endosome; retromer complex; early endosome; midbody; endosome Molecular Function:protein binding Biological Process: protein transport; cell division; cell cycle; regulation of cytokinesis |
| UniProt Code: | Q96C92 |
| NCBI GenInfo Identifier: | 172045853 |
| NCBI Gene ID: | 10807 |
| NCBI Accession: | Q96C92.3 |
| UniProt Secondary Accession: | Q96C92,O60525, Q5SXN1, Q5SXN2, Q5SXN3, Q5SXN4, Q5SXN8 Q6V704, Q9NVY5, A6NCP1, |
| UniProt Related Accession: | Q96C92 |
| Molecular Weight: | 412 |
| NCBI Full Name: | Serologically defined colon cancer antigen 3 |
| NCBI Synonym Full Names: | serologically defined colon cancer antigen 3 |
| NCBI Official Symbol: | SDCCAG3 |
| NCBI Official Synonym Symbols: | NY-CO-3 |
| NCBI Protein Information: | serologically defined colon cancer antigen 3; antigen NY-CO-3 |
| UniProt Protein Name: | Serologically defined colon cancer antigen 3 |
| UniProt Synonym Protein Names: | Antigen NY-CO-3 |
| UniProt Gene Name: | SDCCAG3 |
| UniProt Entry Name: | SDCG3_HUMAN |
| Antibodies | ELISA Kits |
| SDCCAG3 Antibody (PACO12070) | Human SDCCAG3 (Serologically defined colon cancer antigen 3) ELISA Kit |
| Human Serologically defined colon cancer antigen 3 (SDCCAG3) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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