Description
| Antibody Name: | ENTPD8 Antibody (PACO26497) |
| Antibody SKU: | PACO26497 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:2000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human Ectonucleoside triphosphate diphosphohydrolase 8 protein (30-434AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Western Blot Positive WB detected in: Mouse stomach tissue All lanes: ENTPD8 antibody at 2µg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 54, 50 kDa Observed band size: 54 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO26497 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human tonsil tissue using PACO26497 at dilution of 1:100. |
| Background: | Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. |
| Synonyms: | Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8) (EC 3.6.1.5), ENTPD8 |
| UniProt Protein Function: | ENTPD8: Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and UDP, but not toward AMP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Nucleotide Metabolism - pyrimidine; Nucleotide Metabolism - purine; Membrane protein, multi-pass; Hydrolase; Membrane protein, integral; EC 3.6.1.5Chromosomal Location of Human Ortholog: 9q34.3 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q5MY95 |
| NCBI GenInfo Identifier: | 158705943 |
| NCBI Gene ID: | 377841 |
| NCBI Accession: | Q5MY95.2 |
| UniProt Secondary Accession: | Q5MY95,Q6UVZ0, A2BG17 |
| UniProt Related Accession: | Q5MY95 |
| Molecular Weight: | 49,393 Da |
| NCBI Full Name: | Ectonucleoside triphosphate diphosphohydrolase 8 |
| NCBI Synonym Full Names: | ectonucleoside triphosphate diphosphohydrolase 8 |
| NCBI Official Symbol: | ENTPD8 |
| NCBI Official Synonym Symbols: | UNQ2492; GLSR2492; E-NTPDase; NTPDase-8 |
| NCBI Protein Information: | ectonucleoside triphosphate diphosphohydrolase 8 |
| UniProt Protein Name: | Ectonucleoside triphosphate diphosphohydrolase 8 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Ectonucleoside triphosphate diphosphohydrolase |
| UniProt Gene Name: | ENTPD8 |
| UniProt Entry Name: | ENTP8_HUMAN |
| Antibodies |
| ENTPD8 Antibody (PACO09105) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |


