EMR3 Antibody (PACO05532)
- SKU:
- PACO05532
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EMR3 Antibody (PACO05532) |
| Antibody SKU: | PACO05532 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:10000, WB:1:500-1:2000, IF:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Synthesized peptide derived from the C-terminal region of human EMR3. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | EMR3; EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3 |
| UniProt Protein Function: | EMR3: Receptor probably involved in myeloid interactions during immune and inflammatory responses. A ligand for the soluble form of this receptor is present at the surface of momocytes- derived macrophages and activated neutrophils. Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. 3 isoforms of the human protein are produced by alternative splicing.Protein type: GPCR, family 2; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 19p13.1Cellular Component: extracellular space; integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; calcium ion bindingBiological Process: G-protein coupled receptor protein signaling pathway |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the class B seven-span transmembrane (TM7) receptor family expressed predominantly by cells of the immune system. Family members are characterized by an extended extracellular region with a variable number of N-terminal epidermal growth factor (EGF)-like domains coupled to a TM7 domain via a mucin-like spacer domain. This gene is closely linked to the gene encoding egf-like molecule containing mucin-like hormone receptor 2 on chromosome 19. This protein may play a role in myeloid-myeloid interactions during immune and inflammatory responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2014] |
| UniProt Code: | Q9BY15 |
| NCBI GenInfo Identifier: | 133930786 |
| NCBI Gene ID: | 84658 |
| NCBI Accession: | NP_115960.2 |
| UniProt Secondary Accession: | Q9BY15 |
| UniProt Related Accession: | Q9BY15 |
| Molecular Weight: | 6,996 Da |
| NCBI Full Name: | EGF-like module-containing mucin-like hormone receptor-like 3 isoform 1 |
| NCBI Synonym Full Names: | egf-like module containing, mucin-like, hormone receptor-like 3 |
| NCBI Official Symbol: | EMR3 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | EGF-like module-containing mucin-like hormone receptor-like 3; EGF-like module receptor 3; egf-like module-containing mucin-like receptor 3 |
| UniProt Protein Name: | EGF-like module-containing mucin-like hormone receptor-like 3 |
| UniProt Synonym Protein Names: | EGF-like module receptor 3Cleaved into the following 2 chains:EGF-like module-containing mucin-like hormone receptor-like 3 subunit alpha; EGF-like module-containing mucin-like hormone receptor-like 3 subunit beta |
| Protein Family: | |
| UniProt Gene Name: | EMR3 |
| UniProt Entry Name: | EMR3_HUMAN |
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