ELP6 Antibody (PACO52286)
- SKU:
- PACO52286
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ELP6 Antibody (PACO52286) |
| Antibody SKU: | PACO52286 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Elongator complex protein 6 protein (95-195AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human pancreatic cancer using PACO52286 at dilution of 1:100. |
 | Immunofluorescent analysis of PC-3 cells using PACO52286 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. |
| Synonyms: | Elongator complex protein 6 (Angiotonin-transactivated protein 1) (Protein TMEM103), ELP6, ATP1 C3orf75 TMEM103 |
| UniProt Protein Function: | TMEM103: Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Involved in cell migration. Belongs to the ELP6 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 3p21.31Cellular Component: Elongator holoenzyme complexBiological Process: positive regulation of cell migration |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q0PNE2 |
| NCBI GenInfo Identifier: | 121940398 |
| NCBI Gene ID: | 54859 |
| NCBI Accession: | Q0PNE2.1 |
| UniProt Secondary Accession: | Q0PNE2,Q9BW57, Q9NXJ3 |
| UniProt Related Accession: | Q0PNE2 |
| Molecular Weight: | 27,567 Da |
| NCBI Full Name: | Elongator complex protein 6 |
| NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 6 |
| NCBI Official Symbol: | ELP6 |
| NCBI Official Synonym Symbols: | C3orf75; TMEM103 |
| NCBI Protein Information: | elongator complex protein 6 |
| UniProt Protein Name: | Elongator complex protein 6 |
| UniProt Synonym Protein Names: | Angiotonin-transactivated protein 1; Protein TMEM103 |
| Protein Family: | Elongator complex protein |
| UniProt Gene Name: | ELP6 |
| UniProt Entry Name: | ELP6_HUMAN |
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