ELP4 Antibody (PACO09082)
- SKU:
- PACO09082
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ELP4 Antibody (PACO09082) |
| Antibody SKU: | PACO09082 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human ELP4 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | elongation protein 4 homolog (S. cerevisiae);ELP4;C11orf19;FLJ20498;PAX6NEB;PAXNEB;dJ68P15A.1 ; |
| UniProt Protein Function: | ELP4: Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Belongs to the ELP4 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 11p13Cellular Component: nucleoplasm; transcription elongation factor complex; Elongator holoenzyme complex; cytoplasm; histone acetyltransferase complexMolecular Function: protein binding; histone acetyltransferase activity; phosphorylase kinase regulator activityBiological Process: regulation of transcription from RNA polymerase II promoter; establishment and/or maintenance of chromatin architecture; RNA elongation from RNA polymerase II promoter; regulation of protein kinase activityDisease: Aniridia |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. This gene has also been associated with Rolandic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
| UniProt Code: | Q96EB1 |
| NCBI GenInfo Identifier: | 570359562 |
| NCBI Gene ID: | 26610 |
| NCBI Accession: | NP_001275654.1 |
| UniProt Secondary Accession: | Q96EB1,Q9H4E8, Q9NX11, B4E3W0, E7EPZ6 |
| UniProt Related Accession: | Q96EB1 |
| Molecular Weight: | 52,765 Da |
| NCBI Full Name: | elongator complex protein 4 isoform 2 |
| NCBI Synonym Full Names: | elongator acetyltransferase complex subunit 4 |
| NCBI Official Symbol: | ELP4 |
| NCBI Official Synonym Symbols: | AN; hELP4; PAXNEB; PAX6NEB; C11orf19; dJ68P15A.1 |
| NCBI Protein Information: | elongator complex protein 4 |
| UniProt Protein Name: | Elongator complex protein 4 |
| UniProt Synonym Protein Names: | PAX6 neighbor gene protein |
| Protein Family: | Elongator complex protein |
| UniProt Gene Name: | ELP4 |
| UniProt Entry Name: | ELP4_HUMAN |
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