ELOVL1 Antibody (PACO22323)
- SKU:
- PACO22323
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ELOVL1 Antibody (PACO22323) |
| Antibody SKU: | PACO22323 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Synthesized peptide derived from internal of human ELOVL1. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HepG2 cells and Jurkat cells, using ELOVL1 antibody. |
| Background: | Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids (VLCFAs). Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs. |
| Synonyms: | Elongation of very long chain fatty acids protein 1; ELOVL1; SSC1; CGI-88; |
| UniProt Protein Function: | ELOVL1: Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Belongs to the ELO family. |
| UniProt Protein Details: | Protein type:EC 2.3.1.199; Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 1p34.2 Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; membrane Molecular Function:fatty acid elongase activity; protein binding Biological Process: fatty acid elongation, saturated fatty acid; linoleic acid metabolic process; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process |
| UniProt Code: | Q9BW60 |
| NCBI GenInfo Identifier: | 20137931 |
| NCBI Gene ID: | 64834 |
| NCBI Accession: | Q9BW60.1 |
| UniProt Secondary Accession: | Q9BW60,Q53HT2, Q5JUY3, Q8WXU3, Q9NVD9, Q9Y396, B4DP24 |
| UniProt Related Accession: | Q9BW60 |
| Molecular Weight: | 29,485 Da |
| NCBI Full Name: | Elongation of very long chain fatty acids protein 1 |
| NCBI Synonym Full Names: | ELOVL fatty acid elongase 1 |
| NCBI Official Symbol: | ELOVL1 |
| NCBI Official Synonym Symbols: | Ssc1; CGI-88 |
| NCBI Protein Information: | elongation of very long chain fatty acids protein 1 |
| UniProt Protein Name: | Elongation of very long chain fatty acids protein 1 |
| UniProt Synonym Protein Names: | 3-keto acyl-CoA synthase ELOVL1 |
| Protein Family: | Elongation of very long chain fatty acids protein |
| UniProt Gene Name: | ELOVL1 |
| UniProt Entry Name: | ELOV1_HUMAN |
| Antibodies | ELISA Kits |
| ELOVL1 Antibody (PACO00755) | Human Elongation of very long chain fatty acids protein 1 / ELOVL1 ELISA Kit |
| Human Elongation of very long chain fatty acids protein 1 (ELOVL1) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
Related Products
Human Elongation of very long chain fatty acids protein 1 (ELOVL1) ELISA Kit
Human Immunology ELISA Kits 7