ELF1 Transcription Factor Activity Assay
- SKU:
- TFAB00094
- Product Type:
- ELISA Kit
- ELISA Type:
- Transcription Factor Assay
- Analytes:
- ELF1
- Reactivity:
- Human
- Reactivity:
- Mouse
Description
| Product Name: | ELF1 Transcription Factor Activity Assay |
| Product Code: | TFAB00094 |
| Target: | ELF1 |
| Synonyms: | E74-like factor 1 |
| Reactivity: | Human, Mouse |
| Sample Types: | Nuclear or cell lysates |
The Assay Genie ELF1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
| Assay Time: | 4.5 hours |
| Detection Method: | Colorimetric 450 nm |
| Size: | 12 x 8-Well Microstrips |
| Storage: | 4°C for 6 months |
| UniProt Protein Function: | Elf-1: Transcription factor that activates the LYN and BLK promoters. Appears to be required for the T-cell-receptor-mediated trans activation of HIV-2 gene expression. Binds specifically to two purine-rich motifs in the HIV-2 enhancer. Belongs to the ETS family. |
| UniProt Protein Details: | Protein type:DNA-binding; Transcription factor Chromosomal Location of Human Ortholog: 13q13 Cellular Component: nucleoplasm; nucleus Molecular Function:protein binding; transcription factor activity Biological Process: transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; negative regulation of T cell receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; cell differentiation; regulation of cytokine production |
| NCBI Summary: | This gene encodes an E26 transformation-specific related transcription factor. The encoded protein is primarily expressed in lymphoid cells and acts as both an enhancer and a repressor to regulate transcription of various genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009] |
| UniProt Code: | P32519 |
| NCBI GenInfo Identifier: | 212288097 |
| NCBI Gene ID: | 1997 |
| NCBI Accession: | P32519.2 |
| UniProt Secondary Accession: | P32519,Q8N6F6, Q9UDE1, B4E2I5, E9PDQ9, |
| UniProt Related Accession: | P32519 |
| Molecular Weight: | 64,929 Da |
| NCBI Full Name: | ETS-related transcription factor Elf-1 |
| NCBI Synonym Full Names: | E74-like factor 1 (ets domain transcription factor) |
| NCBI Official Symbol: | ELF1 |
| NCBI Protein Information: | ETS-related transcription factor Elf-1 |
| UniProt Protein Name: | ETS-related transcription factor Elf-1 |
| UniProt Synonym Protein Names: | E74-like factor 1 |
| Protein Family: | ETS-related transcription factor |
| UniProt Gene Name: | ELF1 |
| UniProt Entry Name: | ELF1_HUMAN |
