ELAVL2/ELAVL4 Antibody (PACO23213)
- SKU:
- PACO23213
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ELAVL2/ELAVL4 Antibody (PACO23213) |
| Antibody SKU: | PACO23213 |
| Size: | 100ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from internal of human ELAV2/4. |
| Form: | Liquid |
| Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot analysis of extracts from HUVEC cells and Jurkat cells, using ELAV2/4 antibody. |
 | Immunofluorescence analysis of HepG2 cells, using ELAV2/4 antibody. |
| Background: | Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR. |
| Synonyms: | ELAV-like protein 4; Paraneoplastic encephalomyelitis antigen HuD; Hu-antigen D; ELAVL4; HUD |
| UniProt Protein Function: | ELAVL2: Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR. Belongs to the RRM elav family. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:RNA-binding Chromosomal Location of Human Ortholog: 9p21.3 Cellular Component: nucleoplasm Molecular Function:mRNA 3'-UTR binding; protein binding; RNA binding Biological Process: nuclear mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent |
| NCBI Summary: | The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010] |
| UniProt Code: | Q12926 |
| NCBI GenInfo Identifier: | 93141258 |
| NCBI Gene ID: | 1993 |
| NCBI Accession: | Q12926.2 |
| UniProt Secondary Accession: | Q12926,Q13235, Q59G15, Q8NEM4, Q9H1Q8, D3DRK3, |
| UniProt Related Accession: | Q12926 |
| Molecular Weight: | 40kDa |
| NCBI Full Name: | ELAV-like protein 2 |
| NCBI Synonym Full Names: | ELAV like RNA binding protein 2 |
| NCBI Official Symbol: | ELAVL2 |
| NCBI Official Synonym Symbols: | HUB; HELN1; HEL-N1 |
| NCBI Protein Information: | ELAV-like protein 2 |
| UniProt Protein Name: | ELAV-like protein 2 |
| UniProt Synonym Protein Names: | ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1 |
| Protein Family: | ELAV-like protein |
| UniProt Gene Name: | ELAVL2 |
| Antibodies |
| ELAVL2/ELAVL4 Antibody (PACO02632) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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