Name: ELAVL2/ELAVL4 Antibody (PACO23213)
SKU: PACO23213
Availability: OutOfStock

Antibody Name:	ELAVL2/ELAVL4 Antibody (PACO23213)
Antibody SKU:	PACO23213
Size:	100ul
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IF
Recommended Dilutions:	ELISA:1:2000-1:10000, WB:1:500-1:3000, IF:1:100-1:500
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from internal of human ELAV2/4.

Form:	Liquid
Storage Buffer:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western blot analysis of extracts from HUVEC cells and Jurkat cells, using ELAV2/4 antibody.
	Immunofluorescence analysis of HepG2 cells, using ELAV2/4 antibody.

Background:	Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR.
Synonyms:	ELAV-like protein 4; Paraneoplastic encephalomyelitis antigen HuD; Hu-antigen D; ELAVL4; HUD

UniProt Protein Function:	ELAVL2: Binds RNA. Seems to recognize a GAAA motif. Can bind to its own 3'-UTR, the FOS 3'-UTR and the ID 3'-UTR. Belongs to the RRM elav family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:	Protein type:RNA-binding Chromosomal Location of Human Ortholog: 9p21.3 Cellular Component: nucleoplasm Molecular Function:mRNA 3'-UTR binding; protein binding; RNA binding Biological Process: nuclear mRNA splicing, via spliceosome; regulation of transcription, DNA-dependent
NCBI Summary:	The protein encoded by this gene is a neural-specific RNA-binding protein that is known to bind to several 3' UTRs, including its own and also that of FOS and ID. The encoded protein may recognize a GAAA motif in the RNA. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]
UniProt Code:	Q12926
NCBI GenInfo Identifier:	93141258
NCBI Gene ID:	1993
NCBI Accession:	Q12926.2
UniProt Secondary Accession:	Q12926,Q13235, Q59G15, Q8NEM4, Q9H1Q8, D3DRK3,
UniProt Related Accession:	Q12926
Molecular Weight:	40kDa
NCBI Full Name:	ELAV-like protein 2
NCBI Synonym Full Names:	ELAV like RNA binding protein 2
NCBI Official Symbol:	ELAVL2
NCBI Official Synonym Symbols:	HUB; HELN1; HEL-N1
NCBI Protein Information:	ELAV-like protein 2
UniProt Protein Name:	ELAV-like protein 2
UniProt Synonym Protein Names:	ELAV-like neuronal protein 1; Hu-antigen B; HuB; Nervous system-specific RNA-binding protein Hel-N1
Protein Family:	ELAV-like protein
UniProt Gene Name:	ELAVL2