EIPR1 Antibody (PACO36094)
- SKU:
- PACO36094
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EIPR1 Antibody (PACO36094) |
| Antibody SKU: | PACO36094 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human EARP and GARP complex-interacting protein 1 protein (201-387AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human small intestine tissue using PACO36094 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO36094 at dilution of 1:100. |
| Background: | Acts as a component of endosomal retrieval machinery that is involved in protein transport from early endosomes to either recycling endosomes or the trans-Golgi network. Mediates the recruitment of Golgi-associated retrograde protein (GARP) complex to the trans-Golgi network and controls early endosome-to-Golgi transport of internalized protein. Promotes the recycling of internalized transferrin receptor (TFRC) to the plasma membrane through interaction with endosome-associated recycling protein (EARP) complex. |
| Synonyms: | EARP and GARP complex-interacting protein 1 (Endosome-associated recycling protein-interacting protein) (Golgi-associated retrograde protein-interacting protein) (Tumor-suppressing STF cDNA 1 protein) (Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein), EIPR1, TSSC1 |
| UniProt Protein Function: | TSSC1: Chromosomal Location of Human Ortholog: 2p25.3 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene has been reported in PMID 9403053 as one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. Alignment of this gene to genomic sequence data suggests that this gene resides on chromosome 2 rather than chromosome 11. [provided by RefSeq, Dec 2008] |
| UniProt Code: | Q53HC9 |
| NCBI GenInfo Identifier: | 84029603 |
| NCBI Gene ID: | 7260 |
| NCBI Accession: | Q53HC9.2 |
| UniProt Secondary Accession: | Q53HC9,O43179, Q53S19, Q53SG2, D6W4Y1 |
| UniProt Related Accession: | Q53HC9 |
| Molecular Weight: | 43,603 Da |
| NCBI Full Name: | Protein TSSC1 |
| NCBI Synonym Full Names: | tumor suppressing subtransferable candidate 1 |
| NCBI Official Symbol: | TSSC1 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | protein TSSC1 |
| UniProt Protein Name: | Protein TSSC1 |
| UniProt Synonym Protein Names: | Tumor-suppressing STF cDNA 1 protein; Tumor-suppressing subchromosomal transferable fragment candidate gene 1 protein |
| Protein Family: | Protein |
| UniProt Gene Name: | TSSC1 |
| UniProt Entry Name: | TSSC1_HUMAN |
| Antibodies |
| TSSC1 Antibody (PACO05259) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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