EGFL8 Antibody (PACO14367)
- SKU:
- PACO14367
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EGFL8 Antibody (PACO14367) |
| Antibody SKU: | PACO14367 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Fusion protein of human EGFL8 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO14367(EGFL8 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO14367(EGFL8 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: x200). |
| Background: | The epidermal growth factor (EGF) repeat-containing proteins constitute an expanding family of proteins that are involved in several cellular activities, such as blood coagulation, fibrinolysis, cell adhesion, and neural and vertebrate development. EGFL8 (EGF-like domain-containing protein 8), also known as C6orf8, NG3 and VE-statin-2, is a 293 amino acid, secreted protein that contains two EGF-like domains and one EMI domain. Via its EGF and EMI domains, EGFL8 may participate in protein-protein interactions that correlate with cellular proliferation and developmental signaling events. In mice, EGFL8 is expressed predominately in brain, kidney, lung and thymus. |
| Synonyms: | EGF-like-domain, multiple 8 |
| UniProt Protein Function: | EGFL8: Protein type: Calcium-binding; Membrane protein, integral; Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 6p21.32Cellular Component: extracellular regionMolecular Function: calcium ion bindingBiological Process: in utero embryonic development |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q99944 |
| NCBI GenInfo Identifier: | 13449287 |
| NCBI Gene ID: | 80864 |
| NCBI Accession: | NP_085155.1 |
| UniProt Secondary Accession: | Q99944,Q5JP23, Q5SSX3, Q8IV30, B0S884, G5E9Q0 |
| UniProt Related Accession: | Q99944 |
| Molecular Weight: | 32,262 Da |
| NCBI Full Name: | epidermal growth factor-like protein 8 |
| NCBI Synonym Full Names: | EGF-like-domain, multiple 8 |
| NCBI Official Symbol: | EGFL8 |
| NCBI Official Synonym Symbols: | NG3; C6orf8 |
| NCBI Protein Information: | epidermal growth factor-like protein 8; VE-statin-2; EGF-like protein 8; vascular endothelial statin-2 |
| UniProt Protein Name: | Epidermal growth factor-like protein 8 |
| UniProt Synonym Protein Names: | Vascular endothelial statin-2; VE-statin-2 |
| Protein Family: | Epidermal growth factor-like protein |
| UniProt Gene Name: | EGFL8 |
| UniProt Entry Name: | EGFL8_HUMAN |
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