Description
Antibody Name: | EGFL6 Antibody (PACO37690) |
Antibody SKU: | PACO37690 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:2000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Epidermal growth factor-like protein 6 protein (301-554AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot. All lanes: EGFL6 antibody at 6µg/ml. Lane 1: K562 whole cell lysate. Lane 2: Jurkat whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 62 kDa. Observed band size: 62 kDa. |
![]() | Immunohistochemistry of paraffin-embedded human pancreatic tissue using PACO37690 at dilution of 1:100. |
Background: | May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly (By similarity). |
Synonyms: | Epidermal growth factor-like protein 6 (EGF-like protein 6) (MAM and EGF domains-containing gene protein), EGFL6, MAEG |
UniProt Protein Function: | EGFL6: May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly. Belongs to the nephronectin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: Xp22Cellular Component: extracellular space; membrane; basement membraneMolecular Function: integrin binding; calcium ion bindingBiological Process: extracellular matrix organization and biogenesis; multicellular organismal development; cell cycle; cell adhesion; cell differentiation |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IUX8 |
NCBI GenInfo Identifier: | 268607667 |
NCBI Gene ID: | 25975 |
NCBI Accession: | NP_001161362.1 |
UniProt Secondary Accession: | Q8IUX8,Q6UXJ1, Q8NBV0, Q8WYG3, Q9NY67, Q9NZL7, Q9UFK6 B2RCB1 |
UniProt Related Accession: | Q8IUX8 |
Molecular Weight: | 61,388 Da |
NCBI Full Name: | epidermal growth factor-like protein 6 isoform 2 |
NCBI Synonym Full Names: | EGF-like-domain, multiple 6 |
NCBI Official Symbol: | EGFL6 |
NCBI Official Synonym Symbols: | W80; MAEG |
NCBI Protein Information: | epidermal growth factor-like protein 6 |
UniProt Protein Name: | Epidermal growth factor-like protein 6 |
UniProt Synonym Protein Names: | MAM and EGF domains-containing gene protein |
Protein Family: | Epidermal growth factor-like protein |
UniProt Gene Name: | EGFL6 |
UniProt Entry Name: | EGFL6_HUMAN |