EGFL6 Antibody (PACO14366)
- SKU:
- PACO14366
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | EGFL6 Antibody (PACO14366) |
| Antibody SKU: | PACO14366 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:1000-1:2000, WB:1:200-1:1000 |
| Species Reactivity: | Human |
| Immunogen: | Fusion protein of human EGFL6 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Human fetal brain tissue, Primary antibody: PACO14366(EGFL6 Antibody) at dilution 1/450, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. |
| Background: | This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. |
| Synonyms: | EGF-like-domain, multiple 6 |
| UniProt Protein Function: | EGFL6: May bind integrin alpha-8/beta-1 and play a role in hair follicle morphogenesis. Promotes matrix assembly. Belongs to the nephronectin family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: Xp22Cellular Component: extracellular space; membrane; basement membraneMolecular Function: integrin binding; calcium ion bindingBiological Process: extracellular matrix organization and biogenesis; multicellular organismal development; cell cycle; cell adhesion; cell differentiation |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the epidermal growth factor (EGF) repeat superfamily. Members of this superfamily are characterized by the presence of EGF-like repeats and are often involved in the regulation of cell cycle, proliferation, and developmental processes. The gene product contains a signal peptide, suggesting that it is secreted; an EGF repeat region consisting of 4 complete EGF-like repeats and 1 partial EGF-like repeat, 3 of which have a calcium-binding consensus sequence; an arg-gly-asp integrin association motif; and a MAM domain, which is believed to have an adhesive function. This gene is expressed early during development, and its expression has been detected in lung and meningioma tumors. [provided by RefSeq, Jul 2008] |
| UniProt Code: | Q8IUX8 |
| NCBI GenInfo Identifier: | 268607667 |
| NCBI Gene ID: | 25975 |
| NCBI Accession: | NP_001161362.1 |
| UniProt Secondary Accession: | Q8IUX8,Q6UXJ1, Q8NBV0, Q8WYG3, Q9NY67, Q9NZL7, Q9UFK6 B2RCB1 |
| UniProt Related Accession: | Q8IUX8 |
| Molecular Weight: | 61,388 Da |
| NCBI Full Name: | epidermal growth factor-like protein 6 isoform 2 |
| NCBI Synonym Full Names: | EGF-like-domain, multiple 6 |
| NCBI Official Symbol: | EGFL6 |
| NCBI Official Synonym Symbols: | W80; MAEG |
| NCBI Protein Information: | epidermal growth factor-like protein 6 |
| UniProt Protein Name: | Epidermal growth factor-like protein 6 |
| UniProt Synonym Protein Names: | MAM and EGF domains-containing gene protein |
| Protein Family: | Epidermal growth factor-like protein |
| UniProt Gene Name: | EGFL6 |
| UniProt Entry Name: | EGFL6_HUMAN |
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