EDEM1 Polyclonal Antibody
- SKU:
- CAB10579
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | EDEM1 Polyclonal Antibody |
| Product Code: | CAB10579 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal, 50% glycerol, pH7.3. |
| Cellular Location: | Endoplasmic reticulum membrane, Single-pass type II membrane protein |
Enables mannosyl-oligosaccharide 1, 2-alpha-mannosidase activity and misfolded protein binding activity. Involved in mannose trimming involved in glycoprotein ERAD pathway; positive regulation of retrograde protein transport, ER to cytosol; and protein targeting to ER. Located in aggresome and endoplasmic reticulum quality control compartment.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 468-657 of human EDEM1 (NP_055489.1). |
| Sequence: | RYGAL PERYN WQLQA PDVLF YPLRP ELVES TYLLY QATKN PFYLH VGMDI LQSLE KYTKV KCGYA TLHHV IDKST EDRME SFFLS ETCKY LYLLF DEDNP VHKSG TRYMF TTEGH IVSVD EHLRE LPWKE FFSEE GGQDQ GGKSV HRPKP HELKV INSSS NCNRV PDERR YSLPL KSIYM RQIDQ MVGLI |
| Synonyms: | EDEM |
| Calculated MW: | 74kDa |
| Observed MW: | Refer to figures |
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