Description
| Product Name: | EDA2R Polyclonal Antibody |
| Product Code: | CAB8246 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:2000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Cellular Location: | Membrane, Single-pass type III membrane protein |
The protein encoded by this gene is a type III transmembrane protein of the TNFR (tumor necrosis factor receptor) superfamily, and contains cysteine-rich repeats and a single transmembrane domain. This protein binds to the EDA-A2 isoform of ectodysplasin, which plays an important role in maintenance of hair and teeth. Alternatively spliced transcript variants encodes distinct protein isoforms.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-138 of human EDA2R (NP_068555.1). |
| Sequence: | MDCQE NEYWD QWGRC VTCQR CGPGQ ELSKD CGYGE GGDAY CTACP PRRYK SSWGH HRCQS CITCA VINRV QKVNC TATSN AVCGD CLPRF YRKTR IGGLQ DQECI PCTKQ TPTSE VQCAF QLSLV EADAP TVPPQ EAT |
| Synonyms: | XEDAR, EDAA2R, EDA-A2R, TNFRSF27 |
| Calculated MW: | 33kDa |
| Observed MW: | Refer to figures |