ECEL1 Antibody (PACO45786)
- SKU:
- PACO45786
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | ECEL1 Antibody (PACO45786) |
| Antibody SKU: | PACO45786 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Endothelin-converting enzyme-like 1 protein (425-775AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human kidney tissue using PACO45786 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO45786 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human cervical cancer using PACO45786 at dilution of 1:100. |
| Background: | May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides. |
| Synonyms: | Endothelin-converting enzyme-like 1 (EC 3.4.24.-) (Xce protein), ECEL1, XCE |
| UniProt Protein Function: | ECEL1: May contribute to the degradation of peptide hormones and be involved in the inactivation of neuronal peptides. Belongs to the peptidase M13 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Protease; EC 3.4.24.-; Membrane protein, integralChromosomal Location of Human Ortholog: 2q37.1Cellular Component: integral to plasma membraneMolecular Function: metallopeptidase activityBiological Process: respiratory system processDisease: Arthrogryposis, Distal, Type 5d |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the M13 family of endopeptidases. Members of this family are zinc-containing type II integral-membrane proteins that are important regulators of neuropeptide and peptide hormone activity. Mutations in this gene are associated with autosomal recessive distal arthrogryposis, type 5D. This gene has multiple pseudogenes on chromosome 2. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014] |
| UniProt Code: | O95672 |
| NCBI GenInfo Identifier: | 595763541 |
| NCBI Gene ID: | 9427 |
| NCBI Accession: | NP_001277716.1 |
| UniProt Secondary Accession: | O95672,Q45UD9, Q53RF9, Q6UW86, Q86TH4, Q9NY95 |
| UniProt Related Accession: | O95672 |
| Molecular Weight: | |
| NCBI Full Name: | endothelin-converting enzyme-like 1 isoform 2 |
| NCBI Synonym Full Names: | endothelin converting enzyme like 1 |
| NCBI Official Symbol: | ECEL1 |
| NCBI Official Synonym Symbols: | XCE; DA5D; DINE; ECEX |
| NCBI Protein Information: | endothelin-converting enzyme-like 1 |
| UniProt Protein Name: | Endothelin-converting enzyme-like 1 |
| UniProt Synonym Protein Names: | Xce protein |
| Protein Family: | Endothelin-converting enzyme |
| UniProt Gene Name: | ECEL1 |
| UniProt Entry Name: | ECEL1_HUMAN |
| Antibodies |
| ECEL1 Antibody (PACO08984) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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