Microbiology Recombinant Proteins

E.coli Tryptophan Synthase Recombinant Protein (RPES3431)

(No reviews yet) Write a Review
SKU:
RPES3431
Product Type:
Recombinant Protein
Species:
Escherichia coli
Research Area:
Microbiology

Description

system_update_altDatasheet

E.coli Tryptophan Synthase Recombinant Protein

Tryptophan synthase is a multienzyme ?2β2 complex composed of two protein subunit. Tryptophan synthase catalyzes the last two steps in the synthesis of L-tryptophan (L-Trp). The ?-subunit catalyzes cleavage of 3-indole-d-glycerol 3?-phosphate (IGP) to give indole and D-glyceraldehyde 3?-phosphate (G3P). Indole is then transferred through a 25-? hydrophobic tunnel to the β-subunit. The β2 subunit contains pyridoxal 5'-phosphate and catalyzes several pyridoxal 5'-phosphate-dependent reactions, including/3-elimination reactions 6 and a thiol-dependent transamination reaction. This enzyme is commonly found in Eubacteria, Archaebacteria, Protista, Fungi, and Plantae, but is absent from Animalia. As humans do not have tryptophan synthase, this enzyme has been explored as a potential drug target.

View AllClose

0 Reviews

View AllClose