DYRK2 Polyclonal Antibody
- SKU:
- CAB24467
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
Description
| Product Name: | DYRK2 Polyclonal Antibody |
| Product Code: | CAB24467 |
| Reactivity: | Human |
| Applications: | Western blotting |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Reactivity: | Human |
| Tested Applications: | WB, ELISA |
| Key Applications: | Western blotting |
| Recommended Dilution: | WB 1:500-1:1000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 50% glycerol, pH7.3. |
| Positive Samples: | Saos-2, Daudi, U266 (Low expression control) |
| Cellular Location: | Cytoplasm, Nucleus |
DYRK2 belongs to a family of protein kinases whose members are presumed to be involved in cellular growth and/or development. The family is defined by structural similarity of their kinase domains and their capability to autophosphorylate on tyrosine residues. DYRK2 has demonstrated tyrosine autophosphorylation and catalyzed phosphorylation of histones H3 and H2B in vitro. Two isoforms of DYRK2 have been isolated. The predominant isoform, isoform 1, lacks a 5' terminal insert.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 500-600 of human DYRK2. |
| Sequence: | LKGCD DPLFL DFLKQ CLEWD PAVRM TPGQA LRHPW LRRRL PKPPT GEKTS VKRIT ESTGA ITSIS KLPPP SSSAS KLRTN LAQMT DANGN IQQRT VLPKL V |
| Synonyms: | DYRK2, dual specificity tyrosine-phosphorylation-regulated kinase 2 |
| Calculated MW: | 59kDa/66kDa |
| Observed MW: | 66kDa |
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