Description
system_update_alt Datasheet
Product Name: | DUSP3 Antibody |
Product Sku: | CPAB0208 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human DUSP3 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human DUSP3 amino acids 1-185 purified from Ecoli. |
Clone: | PAT9E6AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | DUSP3 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | DUSP3 belongs to the dual specificity protein phosphatase subfamily which inactivates their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. DUSP3 negatively regulate members of the mitogen-activated protein kinase superfamily that are related to cellular proliferation and differentiation. DUSP3 is expressed in both breast and ovarian tissues and displays activity both for tyrosine-protein phosphate and serine-protein phosphate, but exhibits a strong preference toward phosphotyrosines, specifically dephosphorylates and inactivates ERK1 and ERK2. |
Synonyms: | Dual specificity phosphatase 3, VHR, Vaccinia virus phosphatase VH1-related, Dual specificity protein phosphatase VHR, Vaccinia H1-related phosphatase, serine/threonine specific protein phosphatase, DUSP3. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |