Description
Antibody Name: | DUSP21 Antibody (PACO41334) |
Antibody SKU: | PACO41334 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Dual specificity protein phosphatase 21 protein (1-190AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human testis tissue using PACO41334 at dilution of 1:100. |
Background: | Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. |
Synonyms: | Dual specificity protein phosphatase 21 (EC 3.1.3.16) (EC 3.1.3.48) (Low molecular weight dual specificity phosphatase 21) (LMW-DSP21), DUSP21, LMWDSP21 |
UniProt Protein Function: | DUSP21: Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine. Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.Protein type: EC 3.1.3.16; EC 3.1.3.48; Mitochondrial; Motility/polarity/chemotaxis; Protein phosphatase, dual-specificityChromosomal Location of Human Ortholog: Xp11.4-p11.23Cellular Component: cytoplasm; mitochondrial matrix; nucleusMolecular Function: MAP kinase tyrosine/serine/threonine phosphatase activity; protein binding; protein tyrosine phosphatase activityBiological Process: inactivation of MAPK activity |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the dual specificity phosphatase family, specifically the low molecular weight dual specificity phosphatase family. The encoded protein localizes to both the cytoplasm and the nucleus and functions to remove phosphate groups from phosphotyrosine and phosphothreonine residues.[provided by RefSeq, Mar 2009] |
UniProt Code: | Q9H596 |
NCBI GenInfo Identifier: | 225703077 |
NCBI Gene ID: | 63904 |
NCBI Accession: | NP_071359.3 |
UniProt Secondary Accession: | Q9H596,Q0VDA6, Q6IAJ6, Q6YDQ8 |
UniProt Related Accession: | Q9H596 |
Molecular Weight: | 21,529 Da |
NCBI Full Name: | dual specificity protein phosphatase 21 |
NCBI Synonym Full Names: | dual specificity phosphatase 21 |
NCBI Official Symbol: | DUSP21 |
NCBI Official Synonym Symbols: | LMWDSP21 |
NCBI Protein Information: | dual specificity protein phosphatase 21 |
UniProt Protein Name: | Dual specificity protein phosphatase 21 |
UniProt Synonym Protein Names: | Low molecular weight dual specificity phosphatase 21; LMW-DSP21 |
Protein Family: | Dual specificity phosphatase |
UniProt Gene Name: | DUSP21 |
UniProt Entry Name: | DUS21_HUMAN |