DSCR1 Monoclonal Antibody
- SKU:
- CAB23086
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- IHC
- Applications:
- IF
Description
| Product Name: | DSCR1 Monoclonal Antibody |
| Product Code: | CAB23086 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Immunohistochemistry, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC58928 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | IHC-P, IF/ICC, ELISA |
| Key Applications: | Immunohistochemistry, Immunofluorescence |
| Recommended Dilution: | IHC-P 1:50-1:200, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Cellular Location: | cytoplasm, Nucleus |
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Alternative splicing results in multiple transcript variants.
| Immunogen: | Recombinant protein of human DSCR1. |
| Sequence: | Email for sequence |
| Synonyms: | CSP1, DSC1, RCN1, DSCR1, MCIP1, ADAPT78 |
| Calculated MW: | 28kDa |
| Observed MW: | Refer to figures |
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