DRP1 Monoclonal Antibody
- SKU:
- CAB21968
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IP
Description
| Product Name: | DRP1 Monoclonal Antibody |
| Product Code: | CAB21968 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunoprecipitation |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC54410 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IP, ELISA |
| Key Applications: | Western blotting, Immunoprecipitation |
| Recommended Dilution: | WB 1:500-1:1000, IP 1:2000-1:6000 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | HeLa, PC-12, NIH/3T3 |
| Cellular Location: | Cytoplasm, Cytoplasmic vesicle, Endomembrane system, Golgi apparatus, Membrane, Mitochondrion outer membrane, Peripheral membrane protein, Peroxisome, clathrin-coated pit, cytosol, secretory vesicle, synaptic vesicle membrane |
This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms.
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 561-670 of human DRP1 (NP_036192.2). |
| Sequence: | QDSRR ETKNV ASGGG GVGDG VQEPT TGNWR GMLKT SKAEE LLAEE KSKPI PIMPA SPQKG HAVNL LDVPV PVARK LSARE QRDCE VIERL IKSYF LIVRK NIQDS VPKAV |
| Synonyms: | DLP1, DRP1, DVLP, EMPF, OPA5, EMPF1, DYMPLE, HDYNIV |
| Calculated MW: | 82kDa |
| Observed MW: | 78kDa、82kDa |
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