Description
| Antibody Name: | DRC7 Antibody (PACO37626) |
| Antibody SKU: | PACO37626 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dynein regulatory complex subunit 7 protein (1-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO37626 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO37626 at dilution of 1:100. |
| Background: | Key component of the nexin-dynein regulatory complex (N-DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility. |
| Synonyms: | Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog), DRC7, C16orf50 CCDC135 |
| UniProt Protein Function: | CCDC135: Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility. Belongs to the CCDC135 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 16q21Cellular Component: cytoplasm; cytoskeletonMolecular Function: protein binding |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8IY82 |
| NCBI GenInfo Identifier: | 574584598 |
| NCBI Gene ID: | 84229 |
| NCBI Accession: | NP_001276091.1 |
| UniProt Secondary Accession: | Q8IY82,Q8NAA0, Q9H080, A8K943 |
| UniProt Related Accession: | Q8IY82 |
| Molecular Weight: | 96,300 Da |
| NCBI Full Name: | dynein regulatory complex subunit 7 isoform a |
| NCBI Synonym Full Names: | dynein regulatory complex subunit 7 |
| NCBI Official Symbol: | DRC7 |
| NCBI Official Synonym Symbols: | FAP50; CFAP50; CCDC135; C16orf50 |
| NCBI Protein Information: | dynein regulatory complex subunit 7 |
| UniProt Protein Name: | Dynein regulatory complex subunit 7 |
| UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 135; Coiled-coil domain-containing protein lobo homolog |
| Protein Family: | Dynein regulatory complex |
| UniProt Gene Name: | DRC7 |
| UniProt Entry Name: | DRC7_HUMAN |

