Description
Antibody Name: | DRC7 Antibody (PACO37626) |
Antibody SKU: | PACO37626 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Dynein regulatory complex subunit 7 protein (1-300AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | Antigen Affinity Purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO37626 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO37626 at dilution of 1:100. |
Background: | Key component of the nexin-dynein regulatory complex (N-DRC), essential for N-DRC integrity. Involved in the regulation of flagellar motility. |
Synonyms: | Dynein regulatory complex subunit 7 (Coiled-coil domain-containing protein 135) (Coiled-coil domain-containing protein lobo homolog), DRC7, C16orf50 CCDC135 |
UniProt Protein Function: | CCDC135: Plays a role in the regulation of germ cells differentiation during spermatogenesis, particularly during meiosis and spermiogenesis. May be involved in sperm motility. Belongs to the CCDC135 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: Unknown functionChromosomal Location of Human Ortholog: 16q21Cellular Component: cytoplasm; cytoskeletonMolecular Function: protein binding |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8IY82 |
NCBI GenInfo Identifier: | 574584598 |
NCBI Gene ID: | 84229 |
NCBI Accession: | NP_001276091.1 |
UniProt Secondary Accession: | Q8IY82,Q8NAA0, Q9H080, A8K943 |
UniProt Related Accession: | Q8IY82 |
Molecular Weight: | 96,300 Da |
NCBI Full Name: | dynein regulatory complex subunit 7 isoform a |
NCBI Synonym Full Names: | dynein regulatory complex subunit 7 |
NCBI Official Symbol: | DRC7 |
NCBI Official Synonym Symbols: | FAP50; CFAP50; CCDC135; C16orf50 |
NCBI Protein Information: | dynein regulatory complex subunit 7 |
UniProt Protein Name: | Dynein regulatory complex subunit 7 |
UniProt Synonym Protein Names: | Coiled-coil domain-containing protein 135; Coiled-coil domain-containing protein lobo homolog |
Protein Family: | Dynein regulatory complex |
UniProt Gene Name: | DRC7 |
UniProt Entry Name: | DRC7_HUMAN |