DRAM2 Antibody (PACO44804)
- SKU:
- PACO44804
- Product Type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DRAM2 Antibody (PACO44804) |
| Antibody SKU: | PACO44804 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human, Mouse |
| Immunogen: | Recombinant Human DNA damage-regulated autophagy modulator protein 2 protein (182-266AA) |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Purification Method: | Antigen Affinity Purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot. All lanes: DRAM2 antibody at 3.84µg/ml. Lane 1: Mouse heart tissue. Lane 2: Mouse liver tissue. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 30 kDa. Observed band size: 30 kDa.. |
 | Immunohistochemistry of paraffin-embedded human heart tissue using PACO44804 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human bladder cancer using PACO44804 at dilution of 1:100. |
| Background: | Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1. |
| Synonyms: | DNA damage-regulated autophagy modulator protein 2 (Transmembrane protein 77), DRAM2, TMEM77 |
| UniProt Protein Function: | TMEM77: Induces apoptotic cell death when coexpressed with DRAM1. Belongs to the DRAM/TMEM150 family.Protein type: Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 1p13.3Cellular Component: apical plasma membrane; cytoplasm; Golgi apparatus; intracellular membrane-bound organelle; lysosome; photoreceptor inner segmentBiological Process: photoreceptor cell maintenance; regulation of autophagy; visual perceptionDisease: Cone-rod Dystrophy 21 |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q6UX65 |
| NCBI GenInfo Identifier: | 166235182 |
| NCBI Gene ID: | 128338 |
| NCBI Accession: | NP_848549.3 |
| UniProt Secondary Accession: | Q6UX65,Q4VWF6, Q86VD3, Q8NBQ4, B3SUG9 |
| UniProt Related Accession: | Q6UX65 |
| Molecular Weight: | |
| NCBI Full Name: | DNA damage-regulated autophagy modulator protein 2 |
| NCBI Synonym Full Names: | DNA damage regulated autophagy modulator 2 |
| NCBI Official Symbol: | DRAM2 |
| NCBI Official Synonym Symbols: | CORD21; PRO180; TMEM77; WWFQ154 |
| NCBI Protein Information: | DNA damage-regulated autophagy modulator protein 2 |
| UniProt Protein Name: | DNA damage-regulated autophagy modulator protein 2 |
| UniProt Synonym Protein Names: | Transmembrane protein 77 |
| Protein Family: | DNA damage-regulated autophagy modulator protein |
| UniProt Gene Name: | DRAM2 |
| UniProt Entry Name: | DRAM2_HUMAN |
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