dps Antibody (PACO52138)
- SKU:
- PACO52138
- Product Type:
- Antibody
- Reactivity:
- Bacteria
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | dps Antibody (PACO52138) |
| Antibody SKU: | PACO52138 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Mycobacterium smegmatis |
| Immunogen: | Recombinant Mycobacterium smegmatis DNA protection during starvation protein (1-183AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in Recombinant protein. All lanes: dps antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 36 kDa. Observed band size: 36 kDa. |
| Background: | Protects DNA from oxidative damage by sequestering intracellular Fe(2+) ion and storing it in the form of Fe(3+) oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe(2+) ions, which prevents hydroxyl radical production by the Fenton reaction (By similarity). It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage. |
| Synonyms: | DNA protection during starvation protein (EC 1.16), dps |
| UniProt Protein Function: | Protects DNA from oxidative damage by sequestering intracellular Fe2+ ion and storing it in the form of Fe3+ oxyhydroxide mineral. One hydrogen peroxide oxidizes two Fe2+ ions, which prevents hydroxyl radical production by the Fenton reaction (). It protects DNA from hydroxyl radical-mediated cleavage. Binds DNA with no apparent sequence specificity without self-aggregation nor promotion of DNA condensation. Is unable to protect DNA from DNase-mediated cleavage. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | P0C558 |
| NCBI GenInfo Identifier: | 152013517 |
| NCBI Gene ID: | |
| NCBI Accession: | P0C558.1 |
| UniProt Secondary Accession: | P0C558,Q8VP75 |
| UniProt Related Accession: | P0C558 |
| Molecular Weight: | 36.3 kDa |
| NCBI Full Name: | DNA protection during starvation protein |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | DNA protection during starvation protein |
| UniProt Synonym Protein Names: | |
| Protein Family: | Dehydrodolichyl diphosphate synthase |
| UniProt Gene Name: | dps |
| UniProt Entry Name: | DPS_MYCSM |
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