Description
| Antibody Name: | DOK6 Antibody (PACO08917) |
| Antibody SKU: | PACO08917 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human DOK6 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | docking protein 6;DOK6;DOK5L;HsT3226;MGC20785 ; |
| UniProt Protein Function: | DOK6: ocking proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. Interacts via its PTB domain with phosphorylated Ret, promoting neurite growth. May have a role in brain development and/or maintenance. Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis. |
| UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 18q22.2 Molecular Function:insulin receptor binding; protein binding |
| NCBI Summary: | DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q6PKX4 |
| NCBI GenInfo Identifier: | 84029601 |
| NCBI Gene ID: | 220164 |
| NCBI Accession: | Q6PKX4.1 |
| UniProt Secondary Accession: | Q6PKX4,Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2, A6NNG3, |
| UniProt Related Accession: | Q6PKX4 |
| Molecular Weight: | 38,318 Da |
| NCBI Full Name: | Docking protein 6 |
| NCBI Synonym Full Names: | docking protein 6 |
| NCBI Official Symbol: | DOK6 |
| NCBI Official Synonym Symbols: | DOK5L; HsT3226 |
| NCBI Protein Information: | docking protein 6 |
| UniProt Protein Name: | Docking protein 6 |
| UniProt Synonym Protein Names: | Downstream of tyrosine kinase 6 |
| Protein Family: | Docking protein |
| UniProt Gene Name: | DOK6 |
| UniProt Entry Name: | DOK6_HUMAN |