Description
Antibody Name: | DOK6 Antibody (PACO08917) |
Antibody SKU: | PACO08917 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human DOK6 |
Form: | Liquid |
Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | docking protein 6;DOK6;DOK5L;HsT3226;MGC20785 ; |
UniProt Protein Function: | DOK6: ocking proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. Interacts via its PTB domain with phosphorylated Ret, promoting neurite growth. May have a role in brain development and/or maintenance. Highly expressed in fetal and adult brain. Highly expressed in the cerebellum. Weak expression in kidney, spinal cord and testis. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: 18q22.2 Molecular Function:insulin receptor binding; protein binding |
NCBI Summary: | DOK6 is a member of the DOK (see DOK1; MIM 602919) family of intracellular adaptors that play a role in the RET (MIM 164761) signaling cascade (Crowder et al., 2004 [PubMed 15286081]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6PKX4 |
NCBI GenInfo Identifier: | 84029601 |
NCBI Gene ID: | 220164 |
NCBI Accession: | Q6PKX4.1 |
UniProt Secondary Accession: | Q6PKX4,Q4V9S3, Q8WUZ8, Q96HI2, Q96LU2, A6NNG3, |
UniProt Related Accession: | Q6PKX4 |
Molecular Weight: | 38,318 Da |
NCBI Full Name: | Docking protein 6 |
NCBI Synonym Full Names: | docking protein 6 |
NCBI Official Symbol: | DOK6 |
NCBI Official Synonym Symbols: | DOK5L; HsT3226 |
NCBI Protein Information: | docking protein 6 |
UniProt Protein Name: | Docking protein 6 |
UniProt Synonym Protein Names: | Downstream of tyrosine kinase 6 |
Protein Family: | Docking protein |
UniProt Gene Name: | DOK6 |
UniProt Entry Name: | DOK6_HUMAN |