Description
Antibody Name: | DOCK5 Antibody (PACO41346) |
Antibody SKU: | PACO41346 |
Size: | 50ug |
Host Species: | Rabbit |
Tested Applications: | ELISA |
Recommended Dilutions: | |
Species Reactivity: | Human |
Immunogen: | Recombinant Human Dedicator of cytokinesis protein 5 protein (1-200AA) |
Form: | Liquid |
Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
Purification Method: | >95%, Protein G purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Background: | Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. |
Synonyms: | Dedicator of cytokinesis protein 5, DOCK5 |
UniProt Protein Function: | DOCK5: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Belongs to the DOCK family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; Motility/polarity/chemotaxis; GAPsChromosomal Location of Human Ortholog: 8p21.2Cellular Component: cytoplasmMolecular Function: guanyl-nucleotide exchange factor activityBiological Process: positive regulation of GTPase activity; positive regulation of smooth muscle cell migration; small GTPase mediated signal transduction |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q9H7D0 |
NCBI GenInfo Identifier: | 117553586 |
NCBI Gene ID: | 80005 |
NCBI Accession: | NP_079216.4 |
UniProt Secondary Accession: | Q9H7D0,Q5XKD5, Q6AI11, Q6PJS6, Q6ZTS6, B2RNY0 |
UniProt Related Accession: | Q9H7D0 |
Molecular Weight: | 40,421 Da |
NCBI Full Name: | dedicator of cytokinesis protein 5 |
NCBI Synonym Full Names: | dedicator of cytokinesis 5 |
NCBI Official Symbol: | DOCK5 |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | dedicator of cytokinesis protein 5 |
UniProt Protein Name: | Dedicator of cytokinesis protein 5 |
UniProt Synonym Protein Names: | |
Protein Family: | Dedicator of cytokinesis protein |
UniProt Gene Name: | DOCK5 |
UniProt Entry Name: | DOCK5_HUMAN |