Description
| Antibody Name: | DOCK5 Antibody (PACO41346) |
| Antibody SKU: | PACO41346 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dedicator of cytokinesis protein 5 protein (1-200AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. |
| Synonyms: | Dedicator of cytokinesis protein 5, DOCK5 |
| UniProt Protein Function: | DOCK5: Guanine nucleotide exchange factor (GEF) for Rho and Rac. GEF proteins activate small GTPases by exchanging bound GDP for free GTP. Belongs to the DOCK family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs, Rac/Rho; Motility/polarity/chemotaxis; GAPsChromosomal Location of Human Ortholog: 8p21.2Cellular Component: cytoplasmMolecular Function: guanyl-nucleotide exchange factor activityBiological Process: positive regulation of GTPase activity; positive regulation of smooth muscle cell migration; small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9H7D0 |
| NCBI GenInfo Identifier: | 117553586 |
| NCBI Gene ID: | 80005 |
| NCBI Accession: | NP_079216.4 |
| UniProt Secondary Accession: | Q9H7D0,Q5XKD5, Q6AI11, Q6PJS6, Q6ZTS6, B2RNY0 |
| UniProt Related Accession: | Q9H7D0 |
| Molecular Weight: | 40,421 Da |
| NCBI Full Name: | dedicator of cytokinesis protein 5 |
| NCBI Synonym Full Names: | dedicator of cytokinesis 5 |
| NCBI Official Symbol: | DOCK5 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | dedicator of cytokinesis protein 5 |
| UniProt Protein Name: | Dedicator of cytokinesis protein 5 |
| UniProt Synonym Protein Names: | |
| Protein Family: | Dedicator of cytokinesis protein |
| UniProt Gene Name: | DOCK5 |
| UniProt Entry Name: | DOCK5_HUMAN |