DOCK10 Antibody (PACO38942)
- SKU:
- PACO38942
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DOCK10 Antibody (PACO38942) |
| Antibody SKU: | PACO38942 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dedicator of cytokinesis protein 10 protein (1645-2186AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO38942 at dilution of 1:100. |
| Background: | Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. |
| Synonyms: | Dedicator of cytokinesis protein 10 (Zizimin-3), DOCK10, KIAA0694 ZIZ3 |
| UniProt Protein Function: | DOCK10: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Belongs to the DOCK family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs; GEFs, Rac/Rho; Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 2q36.2Cellular Component: membraneBiological Process: regulation of cell migration |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the dedicator of cytokinesis protein family. Members of this family are guanosine nucleotide exchange factors for Rho GTPases and defined by the presence of conserved DOCK-homology regions. The encoded protein belongs to the D (or Zizimin) subfamily of DOCK proteins, which also contain an N-terminal pleckstrin homology domain. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Mar 2014] |
| UniProt Code: | Q96BY6 |
| NCBI GenInfo Identifier: | 15929124 |
| NCBI Gene ID: | 55619 |
| NCBI Accession: | BC015018 |
| UniProt Secondary Accession: | Q96BY6,O75178, Q9NW06, Q9NXI8, B3FL70 |
| UniProt Related Accession: | Q96BY6 |
| Molecular Weight: | 249,491 Da |
| NCBI Full Name: | Homo sapiens dedicator of cytokinesis 10, mRNA |
| NCBI Synonym Full Names: | dedicator of cytokinesis 10 |
| NCBI Official Symbol: | DOCK10 |
| NCBI Official Synonym Symbols: | ZIZ3; DRIP2; Nbla10300 |
| NCBI Protein Information: | dedicator of cytokinesis protein 10 |
| UniProt Protein Name: | Dedicator of cytokinesis protein 10 |
| UniProt Synonym Protein Names: | Zizimin-3 |
| Protein Family: | Dedicator of cytokinesis protein |
| UniProt Gene Name: | DOCK10 |
| UniProt Entry Name: | DOC10_HUMAN |
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