Description
| Antibody Name: | DNAJB5 Antibody (PACO08881) |
| Antibody SKU: | PACO08881 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Human DNAJB5 |
| Form: | Liquid |
| Storage Buffer: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method: | Antigen Affinity purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Synonyms: | DnaJ (Hsp40) homolog, subfamily B, member 5;DNAJB5;Hsc40;KIAA1045 ; |
| UniProt Protein Function: | DNAJB5: Expressed under normal conditions, its expression can further be increased after various stress treatments. 2 isoforms of the human protein are produced by alternative splicing.Protein type: ChaperoneChromosomal Location of Human Ortholog: 9p13.3Cellular Component: nucleus; cytosolMolecular Function: protein binding; chaperone binding; unfolded protein bindingBiological Process: protein folding; negative regulation of transcription from RNA polymerase II promoter; response to unfolded protein |
| UniProt Protein Details: | |
| NCBI Summary: | This gene encodes a member of the DNAJ heat shock protein 40 family of co-chaperone proteins. The encoded protein contains an N-terminal DNAJ domain and a C-terminal substrate binding domain but lacks the cysteine-rich domain found in other DNAJ family members. In mice, a multi-protein complex containing this protein, thioredoxin 1, and histone deacetylase 4, serves as a master negative regulator of cardiac hypertrophy. [provided by RefSeq, Mar 2017] |
| UniProt Code: | O75953 |
| NCBI GenInfo Identifier: | 18202150 |
| NCBI Gene ID: | 25822 |
| NCBI Accession: | O75953.1 |
| UniProt Secondary Accession: | O75953 |
| UniProt Related Accession: | O75953 |
| Molecular Weight: | |
| NCBI Full Name: | DnaJ homolog subfamily B member 5 |
| NCBI Synonym Full Names: | DnaJ heat shock protein family (Hsp40) member B5 |
| NCBI Official Symbol: | DNAJB5 |
| NCBI Official Synonym Symbols: | Hsc40 |
| NCBI Protein Information: | dnaJ homolog subfamily B member 5 |
| UniProt Protein Name: | DnaJ homolog subfamily B member 5 |
| UniProt Synonym Protein Names: | Heat shock protein Hsp40-2; Heat shock protein Hsp40-3; Heat shock protein cognate 40; Hsc40 |
| Protein Family: | |
| UniProt Gene Name: | DNAJB5 |
| UniProt Entry Name: | DNJB5_HUMAN |