DNAH7 Antibody (PACO46898)
- SKU:
- PACO46898
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DNAH7 Antibody (PACO46898) |
| Antibody SKU: | PACO46898 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dynein heavy chain 7, axonemal protein (730-903AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunofluorescent analysis of HepG2 cells using PACO46898 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). |
| Synonyms: | Dynein heavy chain 7, axonemal (Axonemal β dynein heavy chain 7) (Ciliary dynein heavy chain 7) (Dynein heavy chain-like protein 2) (hDHC2), DNAH7, KIAA0944 |
| UniProt Protein Function: | DNAH7: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Belongs to the dynein heavy chain family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxis; Microtubule-binding; MotorChromosomal Location of Human Ortholog: 2q32.3Cellular Component: microtubule; axonemal dynein complex; ciliumMolecular Function: ATPase activity; microtubule motor activity; calcium ion binding; ATP bindingBiological Process: metabolic process; ciliary or flagellar motility |
| UniProt Protein Details: | |
| NCBI Summary: | DNAH7 is a component of the inner dynein arm of ciliary axonemes (Zhang et al., 2002 [PubMed 11877439]).[supplied by OMIM, Mar 2008] |
| UniProt Code: | Q8WXX0 |
| NCBI GenInfo Identifier: | 151301127 |
| NCBI Gene ID: | 56171 |
| NCBI Accession: | NP_061720.2 |
| UniProt Secondary Accession: | Q8WXX0,O00433, O95492, Q4G152, Q53QX7, Q53S64, Q53T02 Q68CY5, Q8N1Z2, Q9UMS3 |
| UniProt Related Accession: | Q8WXX0 |
| Molecular Weight: | 461,159 Da |
| NCBI Full Name: | dynein heavy chain 7, axonemal |
| NCBI Synonym Full Names: | dynein, axonemal, heavy chain 7 |
| NCBI Official Symbol: | DNAH7 |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | dynein heavy chain 7, axonemal; hDHC2; ciliary dynein heavy chain 7; axonemal dynein heavy chain 7; dynein heavy chain-like protein 2; axonemal beta dynein heavy chain 7; dynein, axonemal, heavy polypeptide 7 |
| UniProt Protein Name: | Dynein heavy chain 7, axonemal |
| UniProt Synonym Protein Names: | Axonemal beta dynein heavy chain 7; Ciliary dynein heavy chain 7; Dynein heavy chain-like protein 2; hDHC2 |
| Protein Family: | Dynein |
| UniProt Gene Name: | DNAH7 |
| UniProt Entry Name: | DYH7_HUMAN |
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