DNAH1 Antibody (PACO47122)
- SKU:
- PACO47122
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DNAH1 Antibody (PACO47122) |
| Antibody SKU: | PACO47122 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Dynein heavy chain 1, axonemal protein (2225-2407AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human prostate cancer using PACO47122 at dilution of 1:100. |
 | Immunofluorescent analysis of HepG2 cells using PACO47122 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
 | Immunohistochemistry of paraffin-embedded human placenta tissue using PACO47122 at dilution of 1:100. |
| Background: | Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly (By similarity). |
| Synonyms: | Dynein heavy chain 1, axonemal (Axonemal β dynein heavy chain 1) (Ciliary dynein heavy chain 1) (Heat shock regulated protein 1) (HSRF-1) (hDHC7), DNAH1, DHC7 DNAHC1 KIAA1410 |
| UniProt Protein Function: | DNAH1: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Belongs to the dynein heavy chain family. 5 isoforms of the human protein are produced by alternative splicing.Protein type: Motility/polarity/chemotaxisChromosomal Location of Human Ortholog: 3p21.1Biological Process: sperm motility |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9P2D7 |
| NCBI GenInfo Identifier: | 197927452 |
| NCBI Gene ID: | 25981 |
| NCBI Accession: | NP_056327.4 |
| UniProt Secondary Accession: | Q9P2D7,O00436, O15435, O95491, Q6ZU48, Q86YK7, Q8TEJ4 Q92863, Q9H8E6, Q9UFW6 |
| UniProt Related Accession: | Q9P2D7 |
| Molecular Weight: | 360,959 Da |
| NCBI Full Name: | dynein heavy chain 1, axonemal |
| NCBI Synonym Full Names: | dynein axonemal heavy chain 1 |
| NCBI Official Symbol: | DNAH1 |
| NCBI Official Synonym Symbols: | HL11; HDHC7; HL-11; DNAHC1; HSRF-1; XLHSRF-1 |
| NCBI Protein Information: | dynein heavy chain 1, axonemal |
| UniProt Protein Name: | Dynein heavy chain 1, axonemal |
| UniProt Synonym Protein Names: | Axonemal beta dynein heavy chain 1; Ciliary dynein heavy chain 1; Heat shock regulated protein 1; HSRF-1; hDHC7 |
| Protein Family: | Dynein |
| UniProt Gene Name: | DNAH1 |
| UniProt Entry Name: | DYH1_HUMAN |
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