Description
Product Name: | DMT1/SLC11A2 Monoclonal Antibody |
Product Code: | CAB23379 |
Reactivity: | Human, Mouse |
Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
Host Species: | Rabbit |
Purification Method: | Affinity purification |
Isotype: | IgG |
Clone No: | ARC59972 |
Reactivity: | Human, Mouse |
Tested Applications: | WB, IF/ICC, IP, ELISA |
Key Applications: | Western blotting, Immunofluorescence, Immunoprecipitation |
Recommended Dilution: | WB 1:500-1:1000, IF/ICC 1:50-1:200, IP 1:500-1:1000 |
Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
Positive Samples: | 293F |
Cellular Location: | Cell membrane, Early endosome, Endosome membrane, Mitochondrion outer membrane, Multi-pass membrane protein |
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 300-400 of human DMT1/SLC11A2 (NP_000608.1) |
Sequence: | SCIAL FVSFI INVFV VSVFA EAFFG KTNEQ VVEVC TNTSS PHAGL FPKDN STLAV DIYKG GVVLG CYFGP AALYI WAVGI LAAGQ SSTMT GTYSG QFVME G |
Synonyms: | DCT1, DMT1, AHMIO1, NRAMP2 |
Calculated MW: | 61KDa/62KDa/64KDa/65KDa |
Observed MW: | 55-100kDa |