DKK3 Monoclonal Antibody
- SKU:
- CAB22126
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- WB
- Applications:
- IF
Description
| Product Name: | DKK3 Monoclonal Antibody |
| Product Code: | CAB22126 |
| Reactivity: | Human, Mouse, Rat |
| Applications: | Western blotting, Immunofluorescence |
| Host Species: | Rabbit |
| Purification Method: | Affinity purification |
| Isotype: | IgG |
| Clone No: | ARC52093 |
| Reactivity: | Human, Mouse, Rat |
| Tested Applications: | WB, IF/ICC, ELISA |
| Key Applications: | Western blotting, Immunofluorescence |
| Recommended Dilution: | WB 1:2000-1:20000, IF/ICC 1:50-1:200 |
| Storage Buffer: | Store at -20°C. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300, 0.05% BSA, 50% glycerol, pH7.3. |
| Positive Samples: | 293T, SH-SY5Y, Mouse brain, Rat brain |
| Cellular Location: | extracellular space |
This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein.
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 22-200 of human DKK3 (NP_056965.3). |
| Sequence: | APAPT ATSAP VKPGP ALSYP QEEAT LNEMF REVEE LMEDT QHKLR SAVEE MEAEE AAAKA SSEVN LANLP PSYHN ETNTD TKVGN NTIHV HREIH KITNN QTGQM VFSET VITSV GDEEG RRSHE CIIDE DCGPS MYCQF ASFQY TCQPC RGQRM LCTRD SECCG DQLCV WGHCT KMAT |
| Synonyms: | RIG, CRRL, REIC |
| Calculated MW: | 38kDa |
| Observed MW: | 55kDa |
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