DIRAS1 Antibody (PACO19575)
- SKU:
- PACO19575
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DIRAS1 Antibody (PACO19575) |
| Antibody SKU: | PACO19575 |
| Size: | 50ul |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC |
| Recommended Dilutions: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Synthetic peptide of human DIRAS1 |
| Form: | Liquid |
| Storage Buffer: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method: | Antigen affinity purification |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO19575(DIRAS1 Antibody) at dilution 1/52, on the right is treated with synthetic peptide. (Original magnification: x200). |
 | The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO19575(DIRAS1 Antibody) at dilution 1/52, on the right is treated with synthetic peptide. (Original magnification: x200). |
| Background: | DIRAS1 (DIRAS family, GTP-binding Ras-like 1), also known as distinct subgroup of the Ras family member 1, RIG (Ras-related inhibitor of cell growth), small GTP-binding tumor suppressor 1 or GBTS1, is a 198 amino acid, cell membrane protein expressed at high levels in brain and heart. DIRAS1 displays low GTPase activity and is encoded by a gene that maps to human chromosome 19p13.3. |
| Synonyms: | DIRAS family, GTP-binding RAS-like 1 |
| UniProt Protein Function: | DIRAS1: Displays low GTPase activity and exist predominantly in the GTP-bound form. Belongs to the small GTPase superfamily. Di-Ras family.Protein type: G protein, monomeric, di-Ras; G protein; G protein, monomericChromosomal Location of Human Ortholog: 19p13.3Cellular Component: plasma membraneMolecular Function: GTP binding; GTPase activity; mitogen-activated protein kinase bindingBiological Process: positive regulation of MAP kinase activity |
| UniProt Protein Details: | |
| NCBI Summary: | DIRAS1 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.[supplied by OMIM, Apr 2004] |
| UniProt Code: | O95057 |
| NCBI GenInfo Identifier: | 62286591 |
| NCBI Gene ID: | 148252 |
| NCBI Accession: | O95057.1 |
| UniProt Secondary Accession: | O95057 |
| UniProt Related Accession: | O95057 |
| Molecular Weight: | 22,329 Da |
| NCBI Full Name: | GTP-binding protein Di-Ras1 |
| NCBI Synonym Full Names: | DIRAS family GTPase 1 |
| NCBI Official Symbol: | DIRAS1 |
| NCBI Official Synonym Symbols: | RIG; GBTS1; Di-Ras1 |
| NCBI Protein Information: | GTP-binding protein Di-Ras1 |
| UniProt Protein Name: | GTP-binding protein Di-Ras1 |
| UniProt Synonym Protein Names: | Distinct subgroup of the Ras family member 1; Ras-related inhibitor of cell growth; Rig; Small GTP-binding tumor suppressor 1 |
| Protein Family: | GTP-binding protein |
| UniProt Gene Name: | DIRAS1 |
| UniProt Entry Name: | DIRA1_HUMAN |
