DHX15 Antibody (PACO56780)
- SKU:
- PACO56780
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DHX15 Antibody (PACO56780) |
| Antibody SKU: | PACO56780 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 protein (371-502AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: 293 whole cell lysate. All lanes: DHX15 antibody at 3.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 91 kDa. Observed band size: 91 kDa. |
| Background: | Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. In cooperation with TFIP11 seem to be involved in the transition of the U2, U5 and U6 snRNP-containing IL complex to the snRNP-free IS complex leading to efficient debranching and turnover of excised introns. |
| Synonyms: | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 (EC 3.6.4.13) (ATP-dependent RNA helicase #46) (DEAH box protein 15), DHX15, DBP1 DDX15 |
| UniProt Protein Function: | DDX15: Pre-mRNA processing factor involved in disassembly of spliceosomes after the release of mature mRNA. Belongs to the DEAD box helicase family. DEAH subfamily. DDX15/PRP43 sub-subfamily.Protein type: EC 3.6.4.13; Helicase; Nucleolus; RNA splicing; RNA-binding; SpliceosomeChromosomal Location of Human Ortholog: 4p15.2Cellular Component: cytoplasm; nuclear speck; nucleolus; nucleoplasm; nucleus; U12-type spliceosomal complex; U2-type post-mRNA release spliceosomal complexMolecular Function: ATP binding; ATP-dependent RNA helicase activity; double-stranded RNA binding; protein binding; RNA binding; RNA helicase activityBiological Process: mRNA processing; mRNA splicing, via spliceosome; response to alkaloid; response to toxin; RNA splicing |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a putative ATP-dependent RNA helicase implicated in pre-mRNA splicing. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O43143 |
| NCBI GenInfo Identifier: | 68509926 |
| NCBI Gene ID: | 1665 |
| NCBI Accession: | NP_001349.2 |
| UniProt Secondary Accession: | O43143,Q9NQT7 |
| UniProt Related Accession: | O43143 |
| Molecular Weight: | 90,933 Da |
| NCBI Full Name: | pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 |
| NCBI Synonym Full Names: | DEAH-box helicase 15 |
| NCBI Official Symbol: | DHX15 |
| NCBI Official Synonym Symbols: | DBP1; HRH2; DDX15; PRP43; PRPF43; PrPp43p |
| NCBI Protein Information: | pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 |
| UniProt Protein Name: | Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 |
| UniProt Synonym Protein Names: | ATP-dependent RNA helicase #46; DEAH box protein 15 |
| Protein Family: | Pre-mRNA-splicing factor ATP-dependent RNA helicase |
| UniProt Gene Name: | DHX15 |
| UniProt Entry Name: |
| Antibodies |
| DHX15 Antibody (PACO08829) |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |
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