DHFR Monoclonal Antibody [PAT5B2AT] (CPAB0210)

Name: DHFR Monoclonal Antibody [PAT5B2AT] (CPAB0210)
SKU: CPAB0210
Availability: OutOfStock

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system_update_alt Datasheet Overview

Immunology Antibodies 2

Immunology Antibodies 3

system_update_alt Datasheet Overview

OverviewProduct Name:SPAM1 Monoclonal AntibodyProduct Code:CAB22178Reactivity:Human, Mouse, RatApplications:Western blotting, Imm

Purification Method:	DHFR antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:	IgG1
Background:	Dihydrofolate reductase (DHFR) is an enzyme that reduces dihydrofolic acid to tetrahydrofolic acid, with NADPH as electron donor that can be converted to the kinds of tetrahydrofolate cofactors applied in 1-carbon transfer chemistry. DHFR converts dihydrofolate into tetrahydrofolate, which is a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and specific amino acids. Even though the functional DHFR gene is mapped to chromosome 5, numerous intronless processed pseudogenes or dihydrofolate reductase-like genes are identified on separate chromosomes. DHFR deficiency is associated with megaloblastic anemia.DHFR knockdown plays a role in the anticancer activity of 2-hydroxyoleic acid. DHFR gene insertion/deletion polymorphism is linked to variation in serum and red blood cell folate concentrations in women.
Synonyms:	Dihydrofolate reductase, DHFR, DHFRP1.
Storage Buffer:	For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Product Name:	DHFR Antibody
Product Sku:	CPAB0210
Size:	5μg
Host Species:	Mouse
Immunogen:	Anti-human DHFR mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human DHFR amino acids 1-187 purified from Ecoli.
Clone:	PAT5B2AT.
Reactivity:	Human
Applications:	Western Blot, ELISA, Flow Cytometry