Description
Antibody Name: | DGKK Antibody (PACO23254) |
Antibody SKU: | PACO23254 |
Size: | 100ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, IHC, IF |
Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:50-1:100, IF:1:100-1:500 |
Species Reactivity: | Human |
Immunogen: | Synthesized peptide derived from C-terminal of human DGKK. |
Form: | Liquid |
Storage Buffer: | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DGKK antibody. |
![]() | Immunofluorescence analysis of COS-7 cells, using DGKK antibody. |
Background: | Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). |
Synonyms: | EC 2.7.1.107; Diglyceride kinase kappa; DGK-kappa; DAG kinase kappa; 142 kDa diacylglycerol kinase |
UniProt Protein Function: | DGKK: Phosphorylates diacylglycerol (DAG) to generate phosphatidic acid (PA). Belongs to the eukaryotic diacylglycerol kinase family.Protein type: EC 2.7.1.107; Kinase, lipidChromosomal Location of Human Ortholog: Xp11.22Cellular Component: cytoplasm; plasma membraneMolecular Function: ATP binding; diacylglycerol kinase activity; metal ion bindingBiological Process: blood coagulation; diacylglycerol metabolic process; phosphorylation; platelet activation; protein kinase C activation; response to oxidative stress |
UniProt Protein Details: | |
NCBI Summary: | The protein encoded by this gene is an enzyme that phosphorylates diacylglycerol, converting it to phosphatidic acid. The encoded protein is a membrane protein and is inhibited by hydrogen peroxide. Variations in this gene have been associated with hypospadias. [provided by RefSeq, Mar 2011] |
UniProt Code: | Q5KSL6 |
NCBI GenInfo Identifier: | 74708075 |
NCBI Gene ID: | 139189 |
NCBI Accession: | Q5KSL6.1 |
UniProt Secondary Accession: | Q5KSL6,B2RP91 |
UniProt Related Accession: | Q5KSL6 |
Molecular Weight: | 141,829 Da |
NCBI Full Name: | Diacylglycerol kinase kappa |
NCBI Synonym Full Names: | diacylglycerol kinase kappa |
NCBI Official Symbol: | DGKK |
NCBI Official Synonym Symbols: | |
NCBI Protein Information: | diacylglycerol kinase kappa |
UniProt Protein Name: | Diacylglycerol kinase kappa |
UniProt Synonym Protein Names: | 142 kDa diacylglycerol kinase; Diglyceride kinase kappa; DGK-kappa |
Protein Family: | Diacylglycerol kinase |
UniProt Gene Name: | DGKK |
UniProt Entry Name: | DGKK_HUMAN |
Antibodies |
DGKK Antibody (PACO03500) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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