DEPDC1B Antibody (PACO53154)
- SKU:
- PACO53154
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Applications:
- WB
- Applications:
- IHC
- Applications:
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DEPDC1B Antibody (PACO53154) |
| Antibody SKU: | PACO53154 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human DEP domain-containing protein 1B protein (343-529AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot. Positive WB detected in: HEK293 whole cell lysate. All lanes: DEPDC1B antibody at 4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 62, 55 kDa. Observed band size: 62 kDa. |
 | Immunohistochemistry of paraffin-embedded human liver cancer using PACO53154 at dilution of 1:100. |
 | Immunohistochemistry of paraffin-embedded human testis tissue using PACO53154 at dilution of 1:100. |
| Background: | cytosol, GTPase activator activity, cell migration, positive regulation of Wnt signaling pathway, regulation of small GTPase mediated signal transduction |
| Synonyms: | DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8), DEPDC1B, XTP8 |
| UniProt Protein Function: | DEPDC1B: 2 isoforms of the human protein are produced by alternative splicing.Protein type: GAPs; GAPs, Rac/RhoChromosomal Location of Human Ortholog: 5q12.1Cellular Component: cytosolMolecular Function: GTPase activator activityBiological Process: cell migration; positive regulation of GTPase activity; positive regulation of Wnt receptor signaling pathway; regulation of small GTPase mediated signal transduction |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q8WUY9 |
| NCBI GenInfo Identifier: | 23393066 |
| NCBI Gene ID: | 55789 |
| NCBI Accession: | AAN31126.1 |
| UniProt Secondary Accession: | Q8WUY9,Q86WJ3, Q8IZY6, Q9NUN3, Q9NW57, A8K3R9, B4DUT4 |
| UniProt Related Accession: | Q8WUY9 |
| Molecular Weight: | 54,726 Da |
| NCBI Full Name: | BRCC3 |
| NCBI Synonym Full Names: | DEP domain containing 1B |
| NCBI Official Symbol: | DEPDC1B |
| NCBI Official Synonym Symbols: | XTP1; BRCC3 |
| NCBI Protein Information: | DEP domain-containing protein 1B |
| UniProt Protein Name: | DEP domain-containing protein 1B |
| UniProt Synonym Protein Names: | HBV X-transactivated gene 8 protein; HBV XAg-transactivated protein 8 |
| Protein Family: | Lys-63-specific deubiquitinase |
| UniProt Gene Name: | DEPDC1B |
| UniProt Entry Name: | DEP1B_HUMAN |
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