DEFB126 Antibody (PACO26209)
- SKU:
- PACO26209
- Product Type:
- Antibody
- Reactivity:
- NHP - Orangutan
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
| Antibody Name: | DEFB126 Antibody (PACO26209) |
| Antibody SKU: | PACO26209 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Pongo pygmaeus |
| Immunogen: | Recombinant Pongo pygmaeus Beta-defensin 126 protein (21-63AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | Has antibacterial activity. |
| Synonyms: | Beta-defensin 126 (Defensin, β 126), DEFB126 |
| UniProt Protein Function: | Highly glycosylated atypical beta-defensin involved in several aspects of sperm function. Facilitates sperm transport in the female reproductive tract and contributes to sperm protection against immunodetection; both functions are probably implicating the negative surface charge provided by its O-linked oligosaccharides in the sperm glycocalyx. Involved in binding of sperm to oviductal epithelial cells to form a sperm reservoir until ovulation. Release from the sperm surface during capacitation and ovaluation by an elevation of oviductal fluid pH is unmasking other surface components and allows sperm to penetrate the cumulus matrix and bind to the zona pellucida of the oocyte. In vitro has antimicrobial activity and may inhibit LPS-mediated inflammation (). |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | A4H244 |
| NCBI GenInfo Identifier: | 152112508 |
| NCBI Gene ID: | |
| NCBI Accession: | A4H244.1 |
| UniProt Secondary Accession: | A4H244 |
| UniProt Related Accession: | A4H244 |
| Molecular Weight: | 32.31kD |
| NCBI Full Name: | Beta-defensin 126 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Beta-defensin 126 |
| UniProt Synonym Protein Names: | Defensin, beta 126 |
| Protein Family: | Beta-defensin |
| UniProt Gene Name: | DEFB126 |
| UniProt Entry Name: | DB126_PONPY |
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